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1.
Sensors (Basel) ; 24(11)2024 May 21.
Artigo em Inglês | MEDLINE | ID: mdl-38894061

RESUMO

Structural health monitoring for roads is an important task that supports inspection of transportation infrastructure. This paper explores deep learning techniques for crack detection in road images and proposes an automatic pixel-level semantic road crack image segmentation method based on a Swin transformer. This method employs Swin-T as the backbone network to extract feature information from crack images at various levels and utilizes the texture unit to extract the texture and edge characteristic information of cracks. The refinement attention module (RAM) and panoramic feature module (PFM) then merge these diverse features, ultimately refining the segmentation results. This method is called FetNet. We collect four public real-world datasets and conduct extensive experiments, comparing FetNet with various deep-learning methods. FetNet achieves the highest precision of 90.4%, a recall of 85.3%, an F1 score of 87.9%, and a mean intersection over union of 78.6% on the Crack500 dataset. The experimental results show that the FetNet approach surpasses other advanced models in terms of crack segmentation accuracy and exhibits excellent generalizability for use in complex scenes.

2.
ACS Appl Mater Interfaces ; 15(19): 23390-23401, 2023 May 17.
Artigo em Inglês | MEDLINE | ID: mdl-37146248

RESUMO

Cs3Bi2I9 (CBI) single crystal (SC) is a promising material for a higher-performance direct X-ray detector. However, the composition of CBI SC prepared by the solution method usually deviates from the ideal stoichiometric ratio, which limits the detector performance. In this paper, based on the finite element analysis method, the growth model of the top-seed solution method has been established, and then the influence of precursor ratio, temperature field, and other parameters on the composition of CBI SC has been simulated. The simulation results were used to guide the growth of the CBI SCs. Finally, a high-quality CBI SC with a stoichiometric ratio of Cs/Bi/I = 2.87:2:8.95 has been successfully grown, and the defect density is as low as 1.03 × 109 cm-3, the carrier lifetime is as high as 16.7 ns, and the resistivity is as high as 1.44 × 1012 Ω·cm. The X-ray detector based on this SC has a sensitivity of 29386.2 µC·Gyair-1 cm-2 at an electric field of 40 V·mm-1, and a low detection limit of 0.36 nGyair·s-1, creating a record for the all-inorganic perovskite materials.

3.
Proc Natl Acad Sci U S A ; 116(9): 3799-3804, 2019 02 26.
Artigo em Inglês | MEDLINE | ID: mdl-30808765

RESUMO

Obsessive-compulsive disorder (OCD) affects ∼1 to 3% of the world's population. However, the neural mechanisms underlying the excessive checking symptoms in OCD are not fully understood. Using viral neuronal tracing in mice, we found that glutamatergic neurons from the basolateral amygdala (BLAGlu) project onto both medial prefrontal cortex glutamate (mPFCGlu) and GABA (mPFCGABA) neurons that locally innervate mPFCGlu neurons. Next, we developed an OCD checking mouse model with quinpirole-induced repetitive checking behaviors. This model demonstrated decreased glutamatergic mPFC microcircuit activity regulated by enhanced BLAGlu inputs. Optical or chemogenetic manipulations of this maladaptive circuitry restored the behavioral response. These findings were verified in a mouse functional magnetic resonance imaging (fMRI) study, in which the BLA-mPFC functional connectivity was increased in OCD mice. Together, these findings define a unique BLAGlu→mPFCGABA→Glu circuit that controls the checking symptoms of OCD.


Assuntos
Tonsila do Cerebelo/metabolismo , Complexo Nuclear Basolateral da Amígdala/metabolismo , Neurônios/metabolismo , Transtorno Obsessivo-Compulsivo/metabolismo , Tonsila do Cerebelo/diagnóstico por imagem , Tonsila do Cerebelo/fisiopatologia , Animais , Complexo Nuclear Basolateral da Amígdala/diagnóstico por imagem , Complexo Nuclear Basolateral da Amígdala/fisiopatologia , Modelos Animais de Doenças , Ácido Glutâmico/metabolismo , Humanos , Imageamento por Ressonância Magnética , Camundongos , Vias Neurais/metabolismo , Vias Neurais/fisiopatologia , Neurônios/patologia , Transtorno Obsessivo-Compulsivo/diagnóstico por imagem , Transtorno Obsessivo-Compulsivo/fisiopatologia , Córtex Pré-Frontal/diagnóstico por imagem , Córtex Pré-Frontal/metabolismo , Córtex Pré-Frontal/fisiopatologia
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