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1.
Br J Radiol ; 94(1125): 20210032, 2021 Sep 01.
Artigo em Inglês | MEDLINE | ID: mdl-33882246

RESUMO

Radiomics is the extraction of a significant number of quantitative imaging features with the aim of detecting information in correlation with useful clinical outcomes. Features are extracted, after delineation of an area of interest, from a single or a combined set of imaging modalities (including X-ray, US, CT, PET/CT and MRI). Given the high dimensionality, the analytical process requires the use of artificial intelligence algorithms. Firstly developed for diagnostic performance in radiology, it has now been translated to radiation oncology mainly to predict tumor response and patient outcome but other applications have been developed such as dose painting, prediction of side-effects, and quality assurance. In gynecological cancers, most studies have focused on outcomes of cervical cancers after chemoradiation. This review highlights the role of this new tool for the radiation oncologists with particular focus on female GU oncology.


Assuntos
Diagnóstico por Imagem/métodos , Neoplasias dos Genitais Femininos/diagnóstico por imagem , Interpretação de Imagem Assistida por Computador/métodos , Radioterapia (Especialidade)/métodos , Feminino , Genitália Feminina/diagnóstico por imagem , Humanos
2.
Abdom Radiol (NY) ; 46(6): 2308-2322, 2021 06.
Artigo em Inglês | MEDLINE | ID: mdl-33174120

RESUMO

Ovarian cancer remains one of the most lethal gynecological cancers in the world despite extensive progress in the areas of chemotherapy and surgery. Many studies have postulated that this is because of the profound heterogeneity that underpins response to therapy and prognosis. Standard imaging evaluation using CT or MRI does not take into account this tumoral heterogeneity especially in advanced stages with peritoneal carcinomatosis. As such, newly emergent fields in the assessment of tumor heterogeneity have been proposed using radiomics to evaluate the whole tumor burden heterogeneity as opposed to single biopsy sampling. This review provides an overview of radiomics, radiogenomics, and proteomics and examines the use of these newly emergent fields in assessing tumor heterogeneity and its implications in ovarian cancer.


Assuntos
Neoplasias Ovarianas , Neoplasias Peritoneais , Carcinoma Epitelial do Ovário , Feminino , Humanos , Imageamento por Ressonância Magnética , Neoplasias Ovarianas/diagnóstico por imagem , Neoplasias Ovarianas/genética , Prognóstico
3.
Curr Oncol Rep ; 21(8): 70, 2019 06 25.
Artigo em Inglês | MEDLINE | ID: mdl-31240403

RESUMO

PURPOSE OF REVIEW: To briefly review the radiomics concept, its applications, and challenges in oncology in the era of precision medicine. RECENT FINDINGS: Over the last 5 years, more than 500 studies have evaluated the role of radiomics to predict tumor diagnosis, genetic pattern, tumor response to therapy, and survival in multiple cancers. This new post-processing method is aimed at extracting multiple quantitative features from the image and converting them into mineable data. Radiomics models developed have shown promising results and may play a role in the near future in the daily patient management especially to assess tumor heterogeneity acting as a whole tumor virtual biopsy. For now, radiomics is limited by its lack of standardization; future challenges will be to provide robust and reproducible metrics extracted from large multicenter databases.


Assuntos
Processamento de Imagem Assistida por Computador/métodos , Neoplasias/diagnóstico por imagem , Inteligência Artificial , Biópsia , Humanos , Processamento de Imagem Assistida por Computador/normas , Processamento de Imagem Assistida por Computador/tendências , Imageamento por Ressonância Magnética , Neoplasias/genética , Neoplasias/patologia , Tomografia por Emissão de Pósitrons , Medicina de Precisão , Radioterapia (Especialidade)/métodos , Tomografia Computadorizada por Raios X
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