Assuntos
Aborto Espontâneo/epidemiologia , Aconselhamento Genético/estatística & dados numéricos , Prontuários Médicos , Sistema de Registros/estatística & dados numéricos , Aborto Espontâneo/genética , Adolescente , Adulto , Feminino , Aconselhamento Genético/métodos , Humanos , Idade Materna , Pessoa de Meia-Idade , Moscou , Gravidez , Estudos RetrospectivosRESUMO
An investigation of the population of modern Siberian city Angarsk was carried out. The sample consisted of 13746 individuals in the age interval from 21 to 60 years old. The population comprises more than 40 nationalities. The percentage of Russians, Ukrainians, Buryats, Byelorussians and Tatars in this population is 86.37, 5.35, 1.91, 1.65 and 1.46, respectively. The incidence of other nationalities does not exceed 1%. Analysis of the distances of birth places for married couples demonstrated the predominance of those in which husband and wife had come from different administrative regions of the country. This implies a significant impact of migration on formation of the new city population. A new qualitative approach to the assessing of assortative mating considering the nationality is presented and it is discovered that assortative mating on the basis of national belonging takes place in all the nationalities taken into analysis: in Russians, Ukrainians, Buryats, Byelorussians and Tatars.
Assuntos
Consanguinidade , Genética Populacional , População Urbana , Adulto , Etnicidade , Humanos , Pessoa de Meia-Idade , Fenótipo , Sibéria , MigrantesRESUMO
A new method is suggested to control the mutation process in man by the dynamics of hereditary pathology frequency. The paper presents data on registration of spontaneous abortions, congenital malformations, Down's syndrome and perinatal death in Angarsk for 10 years (1971-1980). No changes are found in the frequencies of these data. The dynamic analysis of hereditary pathology "units" of mutation origin for 10 years did not show any time trend.