Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 20 de 47
Filtrar
Mais filtros










Base de dados
Intervalo de ano de publicação
1.
Eur J Dent Educ ; 19(2): 107-12, 2015 May.
Artigo em Inglês | MEDLINE | ID: mdl-25040937

RESUMO

INTRODUCTION: Undergraduate dental curricula increasingly aim to address student attitudes towards people with disabilities. This study reports the effectiveness of a comprehensive, blended learning Special Care Dentistry undergraduate programme to change attitudes towards people with disabilities. METHODS: A validated psychometric instrument (ATDP-Form 0) was given as a course evaluation to third-year dental students in the Dublin Dental University Hospital over 3 years from 2010 to 2013, immediately before and after the delivery of a brief comprehensive curriculum in Special Care Dentistry. RESULTS: From a population of 109 students, 100 (91.7%) pre-test and 83 (76.1%) retest responses were analysed. Mean score before the course, for all years, was 74.8 (SD = 14.7), compared with 76.8 (SD = 14.0) for all years after the course. CONCLUSIONS: Dental students in our study had neither particularly positive, or negative attitudes towards people with disabilities. There was no statistically significant difference in student attitudes before and after the educational intervention. This study, therefore, shows that a comprehensive undergraduate blended learning module, which aimed to improve attitudes towards people with disabilities, did not do so, using the described measures within the selected timeframe.


Assuntos
Atitude do Pessoal de Saúde , Assistência Odontológica para a Pessoa com Deficiência , Educação em Odontologia , Estudantes de Odontologia/psicologia , Currículo , Avaliação Educacional , Feminino , Humanos , Irlanda , Masculino , Psicometria , Adulto Jovem
2.
J Laryngol Otol ; 125(7): 724-8, 2011 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-21524328

RESUMO

INTRODUCTION: Rhinophyma is a disfiguring hypertrophy of the skin of the tip of the nose. OBJECTIVE: To assess the new technique of coblation of rhinophyma. STUDY DESIGN: Case series of six patients. RESULTS: All patients had a good cosmetic result. Comparison with existing techniques showed advantages due to the lower tissue temperature involved. CONCLUSION: Coblation of rhinophyma is an effective treatment with few side effects.


Assuntos
Ablação por Cateter/métodos , Rinofima/cirurgia , Administração Cutânea , Idoso , Anti-Infecciosos/administração & dosagem , Ablação por Cateter/instrumentação , Humanos , Masculino , Pessoa de Meia-Idade , Satisfação do Paciente , Cuidados Pós-Operatórios/métodos , Rinofima/tratamento farmacológico , Rinofima/patologia , Rinoplastia/instrumentação , Rinoplastia/métodos , Resultado do Tratamento , Cicatrização/fisiologia
3.
Ear Nose Throat J ; 88(10): E17-22, 2009 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-19826986

RESUMO

We conducted a prospective, quasi-randomized, controlled study to evaluate the incidence of postoperative complications and the degree of long-term patient satisfaction associated with the use or nonuse of a head bandage following otoplasty (pinnaplasty). Our study population was made up of 84 consecutively presenting patients who had undergone bilateral otoplasty (either an antihelical or conchaplasty procedure) for the correction of prominent ears under general anesthesia from January 2000 through March 2005. Patients ranged in age from 5 to 56 years (median: 13); 69 patients (82%) were aged 19 years and younger. Of the 84 patients, 61 (73%) received a postoperative head bandage and 23 (27%) did not. Data on complications were collected prospectively from case notes. Data on long-term satisfaction were obtained prospectively on the basis of answers to a questionnaire survey (90% response rate) in which patients rated their satisfaction on a visual analog scale from 0 (not at all satisfied) to 10 (completely satisfied). We found no significant difference between the head-bandage group and the no-head-bandage group with respect to complication rates (36 and 26%, respectively; p = 0.3) or long-term patient satisfaction scores (6.56 and 8.46; p = 0.09). According to multiple regression analysis, the performance of conchaplasty (as opposed to antihelical procedures) appeared to be the only independent variable that influenced both of the outcomes measures (i.e., fewer complications and greater long-term patient satisfaction). Two independent variables were found to influence long-term patient satisfaction only: the presence/absence of any complication and the individual surgeon who performed the procedure. There was no correlation between individual surgeons and complications. We conclude that the use of a head bandage is not necessary or advantageous following otoplasty for the correction of prominent ears, particularly in patients who have undergone cartilage plication.


Assuntos
Bandagens , Orelha Externa/anormalidades , Orelha Externa/cirurgia , Satisfação do Paciente , Procedimentos de Cirurgia Plástica , Cuidados Pós-Operatórios , Complicações Pós-Operatórias/etiologia , Adolescente , Adulto , Criança , Pré-Escolar , Inglaterra , Feminino , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , Cicatrização/fisiologia
4.
J Laryngol Otol ; 121(1): 28-30, 2007 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-17040601

RESUMO

This paper describes a new application for radiofrequency ablation in head and neck surgery. Two patients with extensive laryngeal papillomata were successfully treated using this technology. The technique is described in detail, highlighting the main benefits of this approach as compared with existing techniques. These advantages include limited damage to underlying tissues and a bloodless field.


Assuntos
Ablação por Cateter/métodos , Neoplasias Laríngeas/cirurgia , Papiloma/cirurgia , Adulto , Feminino , Humanos , Masculino , Resultado do Tratamento
5.
Clin Otolaryngol ; 31(6): 546-9, 2006 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-17184466

RESUMO

The use of laser for stapedotomy was introduced in our department in the year 2002, and since then has taken over the mechanical technique. A total of 85 patients who had undergone primary stapedotomy with either technique are reported with regards to effectiveness and rate of side effects. Although footplate complications were reduced with the laser, short-term hearing outcomes were similar between the two techniques. In four occasions, the surgeon had to switch back to the mechanical technique unexpectedly. Stapedotomy will continue to be performed with the laser in our department, bearing in mind the occasional need for the older technique.


Assuntos
Hospitais de Distrito , Hospitais Gerais , Terapia a Laser/métodos , Auditoria Médica , Procedimentos Cirúrgicos Otológicos/métodos , Cirurgia do Estribo/métodos , Audiometria/métodos , Condução Óssea/fisiologia , Dióxido de Carbono , Audição , Humanos
6.
Clin Otolaryngol ; 31(2): 138-43, 2006 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-16620334

RESUMO

OBJECTIVES: This study aimed to evaluate differences in post-operative pain comparing KTP laser-assisted uvulopalatoplasty without tonsillectomy (LAUP) with a new described surgical method: coblation uvulopalatoplasty with tonsillectomy (CP). We also evaluate the impact of each surgical technique in reduction of snoring loudness. MATERIAL AND METHODS: Single blind randomized-controlled trial. From a population of 41 consecutive patients on the waiting list for uvulopalatoplasty for simple snoring, the study group was reduced to 17 CP and 13 LAUP. Post-operative pain and reduction of snoring loudness were recorded using visual analogue scales (VAS) during the first 15 post-operative days. Post-operative snoring loudness was documented for 1-year period. RESULTS: Both groups had similar post-operative pain during the first seven post-operative days. A statistically significant reduction in post-operative pain was observed in the CP group after day 8, and maintained until the end of the study. Reduction of snoring loudness was significant in both groups, but no differences were observed between them. DISCUSSION: Coblation uvulopalatoplasty compared with LAUP demonstrates a reduction in post-operative pain, significant after the first post-operative week. The collateral thermal injury caused by laser is responsible for the slow-healing rate and maintained post-operative pain. Coblation dissociates tissue at lower temperatures with minimal collateral thermal injury and consequently faster and less painful recovery. Both surgical procedures have significant and similar reduction in snoring loudness. CONCLUSIONS: Both methods are adequate treatment options for snoring. The less painful recovery in CP promotes this surgical technique as our preferred choice for palate surgery.


Assuntos
Terapia a Laser/métodos , Dor Pós-Operatória/etiologia , Palato/cirurgia , Apneia Obstrutiva do Sono/cirurgia , Tonsilectomia/métodos , Úvula/cirurgia , Adulto , Idoso , Feminino , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , Método Simples-Cego , Ronco/cirurgia , Resultado do Tratamento
8.
Clin Otolaryngol ; 30(4): 333-7, 2005 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-16209675

RESUMO

OBJECTIVES: A prospective non-blinded randomized controlled trial to compare the efficacy of Merocel and RapidRhino nasal packs in the treatment of anterior epistaxis. METHODS: Fifty-two consecutive participants admitted with anterior epistaxis refractory to digital pressure or nasal cautery were randomized to treatment using one or other of the nasal packs. Patients who required repacking because of continued bleeding, only the first packs were included in the analysis. Haemostatic properties of the packs were measured by grading bleeding during and after removal of the pack (0-4, where four is uncontrollable) and by noting if the nose was re-packed or not. The difficulty of insertion and removal (graded 0-3 by clinician where 3 is the most difficult) and the participant's perception of discomfort (graded 0-10, where 10 is the worst pain) during insertion and removal of the pack were also measured. RESULTS: For bleeding, the mean values for Merocel and RapidRhino during packing and after pack removal were not significant (P = 0.38 and 0.82 respectively). The mean values of patient discomfort on insertion were 6.9 and 5.0 (P = 0.01), and for discomfort on removal were 4.6 and 3.4 (P = 0.05) respectively. The mean values of insertion graded by the clinician were 1.7 and 0.9 (P = 0.0003), and for removal were 1.4 and 0.4 (P < 0.0001). CONCLUSIONS: RapidRhino and Merocel are equally effective in the control of anterior epistaxis but RapidRhino is significantly more comfortable for the patient and easier for the healthcare worker during insertion and removal.


Assuntos
Epistaxe/terapia , Formaldeído/uso terapêutico , Hemostáticos/uso terapêutico , Álcool de Polivinil/uso terapêutico , Tampões Cirúrgicos , Adulto , Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Satisfação do Paciente , Resultado do Tratamento
10.
Rhinology ; 42(2): 81-4, 2004 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-15224634

RESUMO

OBJECTIVE: The aim was to compare two year outcomes of partial laser turbinectomy in patients with allergic and non-allergic rhinitis with respect to nasal obstruction symptom scores and nasal peak inspiratory flow rates (nPIFR). This has not been reported previously. METHOD: Fifty-four patients underwent partial laser turbinectomy (28 with allergic rhinitis, 26 with non-allergic rhinitis). NPIFR was measured preoperatively, at 3 months and two years postoperatively. A symptom score questionnaire was also completed. RESULTS: Both allergic and non-allergic patients showed a significant improvement in symptom scores and nPIER at three months (n = 54). The improvement in allergic patients was greater. In the 31 patients seen at two years, there was still a significant improvement in median symptom scores but no such improvement in median nPIFR. In allergic patients (n = 18) at two years, there was no significant improvement in symptom and nPIFR scores. Non-allergic patients (n = 13), however, did show sustained significant improvement in these scores (p < 0.05). Eighty-seven percent (26/31) considered the operation successful and would recommend it to others. CONCLUSIONS: Non-allergic patients derive a more sustained improvement in the medium term compared to allergic individuals when undergoing partial laser turbinectomy. The improvement in symptom scores in the group as a whole was still significant.


Assuntos
Terapia a Laser , Rinite Alérgica Perene/cirurgia , Rinite Alérgica Sazonal/cirurgia , Conchas Nasais/cirurgia , Adolescente , Adulto , Idoso , Feminino , Seguimentos , Humanos , Inalação , Masculino , Pessoa de Meia-Idade , Obstrução Nasal/etiologia , Obstrução Nasal/cirurgia , Estudos Prospectivos , Ventilação Pulmonar , Rinite Alérgica Perene/complicações , Rinite Alérgica Sazonal/complicações , Resultado do Tratamento
12.
Laryngoscope ; 113(11): 2010-3, 2003 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-14603065

RESUMO

OBJECTIVES/HYPOTHESIS: Coblation tonsillectomy is a recently introduced surgical technique. To measure its benefits against traditional tonsillectomy techniques, it is necessary to compare their complication rates. The study aims to identify differences in reactionary and secondary hemorrhage proportions, comparing coblation with dissection tonsillectomy. STUDY DESIGN: Prospective observational cohort study. METHODS: Rates of reactionary and delayed postoperative hemorrhage were measured, comparing 844 coblation tonsillectomies with a control group of 743 tonsillectomies performed by blunt dissection with bipolar diathermy hemostasis. RESULTS: The secondary hemorrhage rate with coblation-assisted tonsillectomy was 2.25% compared with 6.19% in the control group (P <.05). The rate of secondary hemorrhage in children following coblation tonsillectomy was 0.95% compared with 4.77% in the control group (P <.05). The difference was also significant (P <.05) in the adult population (4.40% vs. 8.81%, respectively). No difference was found in the reactionary hemorrhage proportions. CONCLUSION: In the study, coblation tonsillectomy was associated with a lesser incidence of delayed hemorrhage, more significantly in the pediatric population. The new technique using tissue coblation for tonsil dissection offers significant advantages in the postoperative period compared with dissection tonsillectomy with bipolar diathermy hemostasis. Coblation is associated with less postoperative pain and early return to daily activities. Also, there are fewer secondary infections of the tonsil bed and significantly lower rates of secondary hemorrhage with coblation. These results and the disposable nature of the coblation equipment promote coblation tonsillectomy as the authors' preferred dissection method.


Assuntos
Hemorragia Pós-Operatória/prevenção & controle , Tonsilectomia/métodos , Adolescente , Adulto , Estudos de Coortes , Estimulação Elétrica/instrumentação , Feminino , Humanos , Masculino , Observação , Hemorragia Pós-Operatória/epidemiologia , Prevalência , Estudos Prospectivos
13.
J Laryngol Otol ; 116(6): 450-2, 2002 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-12385358

RESUMO

Tonsillectomy has been performed by a number of techniques. This double blind randomized controlled study compares the technique of tissue coblation with bipolar dissection for the removal of tonsils in 10 adult patients with a history of chronic tonsillitis. A significant reduction in post-operative pain and more rapid healing of the tonsillar fossae were found in the side removed by tissue coblation. There were no episodes of primary or secondary haemorrhage on either side. This new technique for tonsil removal warrants further study.


Assuntos
Eletrocoagulação/métodos , Tonsilectomia/métodos , Tonsilite/cirurgia , Adolescente , Adulto , Método Duplo-Cego , Feminino , Humanos , Masculino , Dor Pós-Operatória/etiologia , Resultado do Tratamento
15.
Int J Pediatr Otorhinolaryngol ; 61(3): 195-8, 2001 Dec 01.
Artigo em Inglês | MEDLINE | ID: mdl-11700188

RESUMO

OBJECTIVE: Tonsillectomy has been described using a number of techniques. Recently Coblation Technology has been used to remove tonsils with anecdotal evidence of a reduction in post-operative morbidity. In this study we aim to see if there is any difference in post-operative pain, tonsillar fossae healing and return to a normal diet performing tonsillectomy, using tissue coblation compared with standard bipolar dissection. METHODS: A double blind randomised control trial to compare the technique of tissue coblation with standard bipolar dissection to remove tonsils in 38 children on the waiting list for tonsillectomy, with a history of chronic tonsillitis or obstructive tonsils. RESULTS: A significant reduction in post-operative pain was found in the children whose tonsils were removed by tissue coblation (P<0.0001). More rapid healing of the tonsillar fossae was found in the coblation group. Children who had their tonsils removed by coblation were found to return to their normal diet far sooner than those who underwent bipolar dissection. There were no episodes of primary or secondary haemorrhage in either group. CONCLUSIONS: This new technique using tissue coblation for tonsil removal offers significant advantages in the post-operative period, with rapid return to a normal diet and a drastic reduction in analgesic requirements following the surgery.


Assuntos
Criocirurgia/métodos , Tonsilectomia/métodos , Tonsilite/cirurgia , Criança , Pré-Escolar , Criocirurgia/efeitos adversos , Dieta , Feminino , Humanos , Hipertrofia/patologia , Hipertrofia/cirurgia , Masculino , Medição da Dor , Dor Pós-Operatória/etiologia , Recuperação de Função Fisiológica , Fatores de Tempo , Tonsilectomia/efeitos adversos , Tonsilite/patologia , Cicatrização
16.
Auris Nasus Larynx ; 28(4): 349-52, 2001 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-11694381

RESUMO

A 51-year-old female patient was admitted to our outpatient department with a discharging right ear of six months duration and not responding to aural toilet and topical antibiotics. Microscopic examination showed a collection of soggy keratin in the floor of the ear canal. Suction cleaning showed a skin defect of about 7 mm in diameter. A CT scan showed rarefaction in the bony canal. Histological diagnosis following an excision biopsy under general anaesthetic showed Winer's dilated pore. Winer's dilated pore is a hair follicle tumour arising from the pilosebaceous apparatus. Hair follicle tumours are relatively rare and their clinical appearance is commonly non-specific. In spite of their non-specific features, they show a keratotic plug grossly which when removed reveals a skin defect and may show bone erosion occasionally if the underlying structure is bone. These features can be misinterpreted for more serious lesions such as squamous cell carcinoma or basal cell carcinoma of the ear canal that can lead to pursuing a more aggressive line of management for a benign lesion. We present this rare lesion illustrating the pathological features, differential diagnosis and management.


Assuntos
Meato Acústico Externo/diagnóstico por imagem , Neoplasias da Orelha/diagnóstico por imagem , Folículo Piloso , Lesões Pré-Cancerosas/diagnóstico por imagem , Neoplasias das Glândulas Sebáceas/diagnóstico por imagem , Diagnóstico Diferencial , Meato Acústico Externo/patologia , Meato Acústico Externo/cirurgia , Neoplasias da Orelha/patologia , Neoplasias da Orelha/cirurgia , Feminino , Folículo Piloso/patologia , Humanos , Pessoa de Meia-Idade , Neoplasia de Células Basais/diagnóstico por imagem , Neoplasia de Células Basais/patologia , Neoplasia de Células Basais/cirurgia , Neoplasias Epiteliais e Glandulares/diagnóstico por imagem , Neoplasias Epiteliais e Glandulares/patologia , Neoplasias Epiteliais e Glandulares/cirurgia , Lesões Pré-Cancerosas/patologia , Lesões Pré-Cancerosas/cirurgia , Radiografia , Neoplasias das Glândulas Sebáceas/patologia , Neoplasias das Glândulas Sebáceas/cirurgia
18.
Mol Microbiol ; 39(2): 272-85, 2001 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-11136449

RESUMO

Mitochondrial respiration in the African trypanosome undergoes dramatic developmental stage regulation. This requires co-ordinated control of components encoded by both the nuclear genome and the kinetoplast, the unusual mitochondrial genome of these parasites. As a model for understanding the co-ordination of these genomes, we have examined the regulation and mitochondrial import of a nuclear-encoded component of the cytochrome oxidase complex, cytochrome oxidase subunit VI (COXVI). By generating transgenic trypanosomes expressing intact or mutant forms of this protein, we demonstrate that COXVI is not imported using a conventional cleaved presequence and show that sequences at the N-terminus of the protein are necessary for correct mitochondrial sorting. Analyses of endogenous and transgenic COXVI mRNA and protein expression in parasites undergoing developmental stage differentiation demonstrates a temporal order of control involving regulation in the abundance of, first, mRNA and then protein. This represents the first dissection of the regulation and import of a nuclear-encoded protein into the cytochrome oxidase complex in these organisms, which were among the earliest eukaryotes to possess a mitochondrion.


Assuntos
Complexo IV da Cadeia de Transporte de Elétrons/genética , Regulação da Expressão Gênica no Desenvolvimento , Proteínas de Protozoários/metabolismo , RNA de Protozoário/metabolismo , Trypanosoma brucei rhodesiense/enzimologia , Sequência de Aminoácidos , Animais , Northern Blotting , Western Blotting , Fracionamento Celular , Meios de Cultura , Complexo IV da Cadeia de Transporte de Elétrons/metabolismo , Imunofluorescência , Mitocôndrias/enzimologia , Dados de Sequência Molecular , Plasmídeos/genética , Proteínas de Protozoários/genética , RNA de Protozoário/genética , Transfecção , Trypanosoma brucei rhodesiense/genética , Trypanosoma brucei rhodesiense/crescimento & desenvolvimento
19.
Rhinology ; 39(4): 230-2, 2001 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-11826695

RESUMO

The use of a combination of topical and injected anaesthetic and vasoconstrictive agents is widely applied in rhinological practice. To prepare the nose prior to a laser inferior turbinectomy under combined general and local anaesthetic, we routinely spray the nose with 1:1000 epinephrine and inject 2% xylocaine with 1:80.000 epinephrine into each inferior turbinate. With the current climate tending towards evidence based medicine, we were keen to show that our technique of pre-operative nasal preparation was effective. A randomised, double blind, prospective study was carried out, with patients acting as their own control. We found that the injection of 2% xylocaine with 1:80.000 epinephrine did not confer any additional benefit, in terms of blood loss or post-operative pain, in the treatment of these patients. The inferior turbinate that was injected bled more during the procedure than the non-injected side; there was no difference in post-operative discomfort between the 2 sides.


Assuntos
Anestésicos Locais/uso terapêutico , Perda Sanguínea Cirúrgica/prevenção & controle , Epinefrina/uso terapêutico , Terapia a Laser , Lidocaína/uso terapêutico , Dor Pós-Operatória/prevenção & controle , Conchas Nasais/cirurgia , Vasoconstritores/uso terapêutico , Adolescente , Adulto , Método Duplo-Cego , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Prospectivos
20.
Biochem Soc Trans ; 28(5): 531-6, 2000 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-11044369

RESUMO

Differentiation between bloodstream and tsetse midgut procyclic forms during the life cycle of the African trypanosome is an attractive model for the analysis of stage-regulated events. In particular, this transformation occurs synchronously, there are well-defined markers for stage-regulated processes and cell lines with specific defects in differentiation have been identified. This combination of tools, combined with the developing Trypanosoma brucei genome database is allowing its underlying controls to be investigated at the molecular and cytological levels. This paper examines some recent discoveries that illuminate some of the key events during trypanosome life-cycle progression.


Assuntos
Regulação da Expressão Gênica , Genes de Protozoários , Trypanosoma brucei brucei/crescimento & desenvolvimento , Trypanosoma brucei brucei/genética , Animais , Diferenciação Celular/genética , Genoma de Protozoário , Mutação
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA
...