[Staphylococcal anatoxin, an alternative in the treatment of endogenous uveitis]. / Anatoxina stafilococica, o alternativa în tratamentul uveitei endogene.

The paper presents one clinical study effected by fourty-four patients with endogenous uveitis which beneficiary of a general treatment with staphylococcal anatoxin. The conclusions of the study impose that one effective treatment is obtained at the young patients with anterior, acute uveitis with moderate inflammatory phenomenon and what present one effective answer of the lymphocyte T by interleukin 1. The application of the treatment suppose several exams reminiscent of the immunologic status especially of the cellular immunology.

[Endogenous uveitis. Retrospective clinical study]. / Uveita endogena. Studiu clinic retrospectiv.

The paper proposes one retrospective study of cases with endogenous uveitis hospitalized and treated in Ophthalmological Clinic from Cluj, between 1983-1992. It underlines clinical, therapeutic features. The examination of the group of the patients depending on the treatment underlines the existence of two great therapeutical subgroups: other with nonsteroid antiinflammatory treatment and another with steroid antiinflammatory treatment. Are examined the characteristics of patients, disease and treatment as well its efficiency. Because approximately 25% from patients had a constant functional evolution and 18-20% had low visual acuity, it required the necessity of search some new therapeutical alternative and diversifying of the etiologic exams.

[The mechanisms and mediators of ocular inflammation]. / Mecanisme si mediatori ai inflamatiei oculare.

The humoral and cellular immunity responses are essential components of the inflammation. The inflammation mediators are substances existent in the extracellular medium which achieve the communication between different cells that participate at the inflammatory of immunologic reaction. The humoral mediators (the complement, chinine, coagulation and fibrinolysis systems) come from the activation by other mediators of inactive humoral precursors. The cellular mediators (histamine, serotonin, arachidonic acid metabolites, lymphokines) are freed by cells, activated by other mediators. Some are performed in these cells, other are neoformed. An important role during ocular inflammation is played by oxygen free radicals and bacterial endotoxins.

[The immunological mechanisms of the tissue lesions in endogenous uveitis]. / Mecanismele imunologice ale leziunilor tisulare în uveita endogena.

The endogenous uveitis is essentially an immunologic disease, although it has a very variable immunology. During the immune response are implied the reactions of tardive hypersensibility (by immune complexes), hypersensibility through antibodies produced intraocularly or transported by the overall circulation and rarely, immediate hypersensibility reaction. The absence of lymphatics in the eye and of the antigenic cells in the tissues which limit the anterior chamber, implies an active, deviated immunity response, denoted by the term ACAID.

[The functional anatomy of the eye with its impact on immunopathology]. / Anatomia functionala a ochiului cu incidenta asupra imunopatologiei.

The description of specific eye's functional anatomy from an immunological point of view helps us in better understanding the particularities of immunitary reaction at this level. Unlike the globe appendices (lid, conjunctive and lacrimal apparatus), where the immunitary defense has no particularities, the ocular globe is distinguished by the existence of the hemato-ocular barriers, the absence of lymphatic drainage and the unequal distribution of HLA phenomena in ocular tissues.

[Perforated post-bulbar ulcer. Anatomoclinical characteristics and surgical treatment]. / Ulcerul postbulbar perforat. Particularitati anatomoclinice si de tratament chirurgical.

A total of 59 clinical observations were analyzed, dealing with perforated post-bulbar ulceration. The patients were hospitalized and underwent surgery in the Clinic for Surgery of the Emergency Hospital from Bucharest between 1968 and 1979. The frequency of the perforated post-bulbar ulcer, compared to the total number of patients operated for perforated bulbar ulcer over the same period of time was of 1.41%. The important factors were analyzed, which have influenced the clinical evolution and the surgical treatment. These are : age, the interval between the onset of the symptoms and the time of hospitalization, the symptoms presenting on hospitalization, the anatomo-clinical forms which were encountered during surgery, as well as the type of the surgical interventions. The surgical interventions were practiced in accordance with the general and the local conditions of each patient. A death-rate of 5.08% was recorded in the group.