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2.
J Gastroenterol ; 38(7): 695-9, 2003.
Artigo em Inglês | MEDLINE | ID: mdl-12898364

RESUMO

We report the case of a 25-year-old woman with fulminant hepatic failure (FHF). Liver scintigraphy using (99m)Tc-galactosyl human serum albumin (GSA) and (99m)Tc-phytate produced interesting findings; regenerative nodules appeared as nodules of increased accumulation of (99m)Tc-GSA, whereas these nodules were expressed as defects of accumulation of (99m)Tc-phytate. These scintigraphic findings suggested that the functions of hepatocytes in regenerative nodules were maintained, whereas those of Kupffer cells were impaired. Although (99m)Tc-GSA scintigraphy indicated hepatic functional reserve enough to survive, she died despite intensive therapy including plasma exchange. Based on this case, it is recommended that not only (99m)Tc-GSA scintigraphy but also (99m)Tc-phytate scintigraphy is required to evaluate the prognosis of patients with FHF.


Assuntos
Falência Hepática/diagnóstico por imagem , Regeneração Hepática , Fígado/diagnóstico por imagem , Adulto , Feminino , Humanos , Falência Hepática/patologia , Falência Hepática/fisiopatologia , Compostos de Organotecnécio , Ácido Fítico , Cintilografia , Compostos Radiofarmacêuticos , Agregado de Albumina Marcado com Tecnécio Tc 99m , Pentetato de Tecnécio Tc 99m
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