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Ugeskr Laeger ; 186(24)2024 Jun 10.
Artigo em Dinamarquês | MEDLINE | ID: mdl-38903035

RESUMO

In this case report, a 31-year-old woman with heterozygous familial hypercholesterolaemia (FH) underwent treatment with statins and PCSK9 inhibitor but had to discontinue due to elevated creatine kinase levels and neurological and muscular side effects. In 2021, the patient received inclisiran therapy, the first known instance of its application in Denmark. No side effects were reported, and LDL cholesterol levels were significantly reduced. This case report highlights the potential of inclisiran as an effective and well-tolerated treatment for individuals with heterozygous FH.


Assuntos
Inibidores de Hidroximetilglutaril-CoA Redutases , Hiperlipoproteinemia Tipo II , Inibidores de PCSK9 , Humanos , Feminino , Adulto , Hiperlipoproteinemia Tipo II/tratamento farmacológico , Inibidores de Hidroximetilglutaril-CoA Redutases/uso terapêutico , Inibidores de Hidroximetilglutaril-CoA Redutases/efeitos adversos , LDL-Colesterol/sangue , Anticolesterolemiantes/uso terapêutico , Anticolesterolemiantes/efeitos adversos
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