[Hysteroscopic myomectomy: recurrence and satisfaction survey at short- and long-term]. / Myomectomie hystéroscopique: récidive et enquête de satisfaction à court et long terme.

OBJECTIVES: To assess the postoperative results at short- and long-term after hysteroscopic resection of submucosal myoma giving rise to symptoms. PATIENTS AND METHODS: Retrospective study (University Hospital Estaing, Clermont-Ferrand, France) including patients operated by hysteroscopy in 2004 for one or more submucosal myomas giving rise to symptoms. A survey concerning relapse of symptoms and patient satisfaction was made by phone 4 and 6 years after surgery. RESULTS: Seventy-two patients (mean age: 45.6 years [18-70]) underwent hysteroscopy. At the time of the first survey, the rate of recurrence was 22% (n=15) with 87.5% of cases of recurrence in the first year. Nineteen percent of the patients needed subsequent treatment. The significant factors for the risk of failure of treatment included younger age, number and large size myoma, intramural extension and incomplete resection. In 2010, the overall failure rate was 31.7% (n=20). Fifty percent of the patients who had an incomplete resection required no further treatment. CONCLUSION: In 70% of cases, hysteroscopic resection remains efficient at long-term. Repeat surgery should not be systematic after incomplete resection. The patients must be fully informed, and especially with respect to the risk factors for recurrence.

Nasal functional modifications after physical exercise: olfactory threshold and peak nasal inspiratory flow.

STATEMENT OF PROBLEM: The respiratory nasal effects of physical exercise have been extensively investigated; on the other hand there are no data regarding olfactory threshold modification after aerobic physical exercise. METHODS: The present prospective study investigated the modifications in nasal respiratory flows and olfactory thresholds after controlled aerobic physical exercise in a cohort of 15 adult, healthy volunteers. The Peak Nasal Inspiratory Flow (PNIF), and the Sniffin' Sticks olfactory threshold test were used for our determinations. MAIN RESULTS: The mean PNIF after physical exercise was significantly higher than the mean PNIF value found before physical exercise. Statistical analysis ruled out any significant difference between mean olfactory thresholds pre vs post physical exercise. PRINCIPAL CONCLUSIONS: These outcomes confirmed PNIF sensitivity and reliability also in determining the changes in nasal patency occurring after physical exercise. The active vasoconstriction of nasal mucosa associated with the reduction of blood flow to the olfactory epithelium due to physical exercise may be compensated for by the increase of olfactory molecules that reach the olfactory mucosa because of nasal mucosal shrinkage: this mechanism could explain the stability of mean olfactory threshold after physical exercise.