1.
J Pharm Sci
; 73(9): 1315-7, 1984 Sep.
Artigo
em Inglês
| MEDLINE
| ID: mdl-6491963
RESUMO
Sodium levothyroxine was determined in bulk drugs, tablets, and injections by high-performance liquid chromatography (HPLC). Levothyroxine was separated from excipients and impurities on a 10-microns cyanoalkyl column using an acetonitrile-water-phosphoric acid mobile phase. The HPLC method is shown to be linear, accurate, and precise, and the results obtained by the HPLC and USP XX methods are compared.