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1.
Front Glob Womens Health ; 4: 1061626, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37275210

RESUMO

Introduction: Cognition is defined as the mental activity or process of learning information and understanding through reason, experience, and the senses. In Sub-Saharan African nations like Ethiopia, such assessments of a pregnant mother's mental health during antenatal care are uncommon procedures. Instead, there is a greater focus on the physical well-being of the woman and her fetus. As a result, this study aimed to evaluate the cognitive deficits and related factors in a pregnant women attending an antenatal care service. Methods: This hospital-based cross-sectional study included 415 pregnant women who were receiving antenatal care at Dilla University Referral Hospital in Dilla, Gedeo Zone, Ethiopia. In this study, respondents were chosen using systematic random sampling, and study participants were interviewed using administered questions to gather pertinent data. This study used the OSLO Social Support Scale, the Alcohol, Smoking, and Substance Involvement Screening Test, and the Mini-Mental Status Examination to assess the social support, cognitive status, and current substance use history of a respondent. Descriptive statistics including frequencies, graphs, and percentages were used to describe the results. A logistic regression analysis was conducted to determine the connection between independent factors and the outcome variable at a 95 percent confidence level and p < 0.05. Result: Among all respondents who came for antenatal care visits, only 24 (5.8%) were unmarried (single, divorced, widowed). The mean age of respondents was 26 years old and 155 (37.3%) had attended secondary school. Variables such as strong social support [0.11 (0.03-0.23), p < 0.02], being a follower of orthodox religion [0.24 (0.12-0.39), p < 0.04], ≥5,000 Ethiopian birr monthly income [0.28 (0.17-0.48), p < 0.02], age >26 years old [1.23 (1.14-2.54), p < 0.04], unplanned pregnancy [2.78 (1.45-4.32), p < 0.02], and rural residence [3.90 (2.23-7.34), p < 0.04] were significantly associated with cognitive impairment at 95% confidence interval and a p-value <0.05. Conclusion: This study found that pregnant women who attended antenatal care experienced a significant reduction in cognitive disorders. Additionally, this study revealed adjustable factors such as unwanted pregnancy, social support, and religiosity. It is preferable to check a pregnant woman's cognitive condition at antenatal services and to follow-up on each additional visit.

2.
PLoS One ; 15(7): e0236154, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32730258

RESUMO

INTRODUCTION: Tuberculosis (TB) is a leading cause of morbidity and mortality in low and middle-income countries. Substance use negatively affects TB treatment outcomes. Our recent study has found that khat use predicted poorer adherence to anti-TB medications. However, there is scarce longitudinal study on predictors of khat use among outpatients with TB, and this study aimed at addressing this research gap. METHODS: From October 2017 to October 2018, 268 outpatients with tuberculosis on DOTs were enrolled in a longitudinal study from 26 health institutions in Southwest Ethiopia. Structured questionnaires translated into local languages (Afaan Oromoo and Amharic) were used to assess khat use. Patients were followed for six months, and data were collected on three occasions during the follow-up. A generalized linear mixed model was used to identify the relation between khat use and predictors. Model fitness was checked using the Bayesian Information Criterion (BIC). Odds ratio (OR) and 95% CI were used to describe the strength of association between the outcome variable and predictors. RESULTS: The overall prevalence of khat use at baseline and first follow up was 39.2% while it was 37.3% at second follow up. Of this, 77.1% and 96.2% of them believed that khat use reduces the side effects of anti-TB medications and symptoms of tuberculosis respectively. In the final model, being male (aOR = 7.0, p-value = 0.001), being government employee (aOR = 0.03, p-value≤0.001) and presence of alcohol use disorders (AUD) (aOR = 2.0, p-value≤0.001) predicted khat use among outpatients with tuberculosis. CONCLUSION: A considerable proportion of patients with TB used khat throughout DOTs and wrongly perceived that it had health benefits. The finding implies that all patients diagnosed with TB should be screened for khat use, and a particular emphasis should be given to males and individuals with a history of alcohol use. Moreover, further studies are needed to assess patients' beliefs regarding the benefits of khat use so that interventions can be developed.


Assuntos
Catha/química , Mycobacterium tuberculosis/efeitos dos fármacos , Transtornos Relacionados ao Uso de Substâncias/epidemiologia , Tuberculose/tratamento farmacológico , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Estudos Transversais , Etiópia/epidemiologia , Feminino , Humanos , Estudos Longitudinais , Masculino , Pessoa de Meia-Idade , Mycobacterium tuberculosis/isolamento & purificação , Prevalência , Fatores de Risco , Inquéritos e Questionários , Tuberculose/microbiologia , Tuberculose/psicologia , Adulto Jovem
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