Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 1 de 1
Filtrar
Mais filtros










Base de dados
Intervalo de ano de publicação
1.
Future Oncol ; 8(9): 1157-65, 2012 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-23030490

RESUMO

AIM: To determine whether an electronic nose can differentiate cultured nonmalignant and malignant prostatic cells from each other and whether the smell print is secreted to the surrounding medium. MATERIALS & METHODS: Prostatic nonmalignant (EP-156T and controls) and malignant (LNCaP) cell lines, as well as conditioned and unconditioned media, were collected. The smell prints of the samples were analyzed by a ChemPro(®) 100 electronic nose device. The data were normalized and dimension reduction was conducted. The samples were classified and misclassification rates were calculated. RESULTS: The electronic nose differentiated the nonmalignant and malignant cell lines from each other, achieving misclassification rates of 2.9-3.6%. Cells did not differ from the conditioned medium but differed from the unconditioned medium (misclassification rates: 0.0-25.6%). CONCLUSION: Malignant and nonmalignant prostatic cell lines have distinct smell prints. Prostatic cancer cells seem to modify the smell print of their medium.


Assuntos
Nariz Eletrônico , Odorantes/análise , Próstata/patologia , Compostos Orgânicos Voláteis/análise , Linhagem Celular Tumoral , Meios de Cultivo Condicionados/análise , Meios de Cultivo Condicionados/química , Humanos , Masculino , Neoplasias da Próstata , Compostos Orgânicos Voláteis/química , Compostos Orgânicos Voláteis/metabolismo
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA
...