Influence of Educational Level and Healthy Habits on the Prevalence of Diabesity in a Spanish Working Population.

BACKGROUND: Diabesity is a growing problem internationally. Taking into account the importance of physical activity and diet in its prevention and treatment, the objective of this study was to delve into the impact of healthy habits on diabesity. METHODS: A descriptive, cross-sectional study was carried out in 386,924 Spanish adult workers. Obesity was determined according to eleven different formulas. Life habits were also valued; sociodemographic variables; and educational level; as well as analytical and clinical variables such as blood pressure and blood glucose levels. The association between the different variables was performed using the chi-square and the Student's t-tests when the samples were independent. A multivariate analysis was performed using the multinomial logistic regression test by calculating the odds ratio and a 95% confidence interval. The Hosmer-Lemeshow goodness-of-fit test was also performed. RESULTS: The overall prevalence of diabesity ranged between 0.3% (95% CI 0.3-0.4) when obesity was assessed according to the abdominal volume index and 8.3% (95% CI 8.2-8.4) when evaluated according to the CUN-BAE (Clínica Universitaria de Navarra Body Adiposity Estimator) formula. The prevalence of diabesity was also higher in workers with a non-heart-healthy diet and in those who did not exercise regularly. CONCLUSIONS: The most disadvantaged socioeconomic classes are those with the highest prevalence of diabesity. It is important to prioritise prevention in populations and communities with the most unfavourable social and environmental conditions to reduce the burden of diabesity.

Agreement between Type 2 Diabetes Risk Scales in a Caucasian Population: A Systematic Review and Report.

Early detection of people with undiagnosed type 2 diabetes (T2D) is an important public health concern. Several predictive equations for T2D have been proposed but most of them have not been externally validated and their performance could be compromised when clinical data is used. Clinical practice guidelines increasingly incorporate T2D risk prediction models as they support clinical decision making. The aims of this study were to systematically review prediction scores for T2D and to analyze the agreement between these risk scores in a large cross-sectional study of white western European workers. A systematic review of the PubMed, CINAHL, and EMBASE databases and a cross-sectional study in 59,042 Spanish workers was performed. Agreement between scores classifying participants as high risk was evaluated using the kappa statistic. The systematic review of 26 predictive models highlights a great heterogeneity in the risk predictors; there is a poor level of reporting, and most of them have not been externally validated. Regarding the agreement between risk scores, the DETECT-2 risk score scale classified 14.1% of subjects as high-risk, FINDRISC score 20.8%, Cambridge score 19.8%, the AUSDRISK score 26.4%, the EGAD study 30.3%, the Hisayama study 30.9%, the ARIC score 6.3%, and the ITD score 3.1%. The lowest agreement was observed between the ITD and the NUDS study derived score (κ = 0.067). Differences in diabetes incidence, prevalence, and weight of risk factors seem to account for the agreement differences between scores. A better agreement between the multi-ethnic derivate score (DETECT-2) and European derivate scores was observed. Risk models should be designed using more easily identifiable and reproducible health data in clinical practice.

Urinary phytate concentration and risk of fracture determined by the FRAX index in a group of postmenopausal women

Background/aim: This study was designed to evaluate the relationship between urinary phytate concentration and risk of fracture at 10 years, determined by using the FRAX model, in women who had undergone menopause within 5 years of the time of enrollment. Materials and methods: Of the 212 postmenopausal women evaluated, 69 were excluded because they had urinary phytate concentrations between 0.51 and 0.99 mg/L. Of the remaining 143 women, 91 had low (≤0.50 mg/L) and 52 had high (≥1.0 mg/L) urinary phytate concentrations. The 10-year risk of fracture was calculated by using the FRAX model. Results: The risks of major osteoporotic fracture and hip fracture were higher in women with low urinary phytate levels (P < 0.001 in both cases). Evaluation of the risk of hip fracture in women with and without risk factors for osteoporosis (e.g., tobacco, alcohol, and drug consumption) and according to urinary phytate concentrations indicated that, among women with no risk factors, those with low and high urinary phytate levels had a range of risks of 0%­0.6% and 0%­0.3%, respectively (P = 0.098). Moreover, among women with at least one risk factor, those with low and high urinary phytate had a range of risks of 0.1%­0.8% and 0.1%­0.4%, respectively (P = 0.002). Similar results were observed when the risks of major osteoporotic fracture were analyzed. Conclusion: These results indicate the relationship of phytate with the risks of major osteoporotic fracture and hip fracture, with these differences being more marked in women with risk factors for osteoporosis. From this study follows the importance of the consumption of phytate-rich products (nuts, legumes, whole cereals) to protect against the risk of fracture in 10 years, mainly in women with risk factors for osteoporosis.

[FINDRISC Test: Relationship between cardiovascular risk parameters and scales in Spanish Mediterranean population]. / Test FINDRISC: relación con parámetros y escalas de riesgo cardiovascular en población mediterránea española.

BACKGROUND: The Finnish Diabetes Risk Score (FINDRISC) questionnaire has been used to assess the risk of type 2 diabetes and metabolic syndrome. The objetive was to assess the relationship between different scales related to cardiovascular risk and FINDRISC questionnaire. METHODS: Values of different anthropometric and clinical parameters (body mass index, waist circumference, waist to height ratio, blood pressure), analytical parameters (lipid profile, blood glucose) and scales related to cardiovascular risk (atherogenic index, metabolic syndrome, REGICOR, SCORE, heart age and vascular age) were determined on the basis of the value of the FINDRISC questionnaire. RESULTS: All analyzed parameters related to cardiovascular risk were getting worse at the same time that the value of the FINDRISC questionnaire increased. CONCLUSIONS: There is a close relationship between FINDRISC questionnaire values and those obtained in the different parameters by which cardiovascular risk was measured directly or indirectly.

Introducción: el Finnish Diabetes Risk Score (test de FINDRISC) se ha empleado para valorar el riesgo de padecer diabetes tipo 2 y síndrome metabólico. El objetivo consistió en valorar la relación entre diferentes escalas relacionadas con el riesgo cardiovascular y el test de FINDRISC. Métodos: se determinaron los valores de difentes parámetros antropométricos, clínicos (índice de masa corporal, perímetro de cintura, índice cintura altura, tensión arterial), analíticos (perfil lipídico y glucemia) y escalas relacionadas con riesgo cardiovascular (indices aterogénicos, síndrome metabólico, REGICOR, SCORE, edad del corazón y edad vascular) según el valor del test de FINDRISC. Resultados: todos los parámetros relacionados con riesgo cardiovascular analizados fueron empeorando a medida que aumentaba el valor del test de FINDRISC. Conclusión: existe una estrecha relación entre los valores del test de FINDRISC y los obtenidos en los diferentes parámetros y escalas que valoran de forma directa o indirecta el riesgo cardiovascular.

Índices aterogénicos en trabajadores de diferentes sectores laborales del área mediterránea española / Atherogenic indices in workers of different occupational sectors of the Spanish Mediterranean area

Introducción: Los índices aterogénicos permiten predecir las enfermedades cardiovasculares ya que reflejan muy bien las interacciones clínicas y metabólicas de las fracciones lipídicas. Material y método: Estudio descriptivo y transversal en 60.798 trabajadores del área mediterránea española en los que se determinan diferentes índices aterogénicos (colesterol/HDL, LDL/HDL, triglicéridos/HDL) y se valora la influencia que tiene en ellos el trabajo en diferentes sectores productivos. Resultados: En las mujeres los valores medios de los diferentes índices aterogénicos son mejores en el sector sanitario, mientras que en los varones lo son en el sector primario. El porcentaje de mujeres trabajadoras con valores bajos es igualmente mayor en el sector sanitario, mientras que en los hombres no hay un sector en el que predominen claramente, observándose los mejores valores en hostelería y sector primario. Conclusión: El reparto de factores de riesgo cardiovascular y los valores de los diferentes índices aterogénicos analizados varían en los diferentes sectores laborales

Introduction: Atherogenic indices predict cardiovascular disease, as they provide a good reflection of the clinical and metabolic interactions of lipid fractions. Material and method: A descriptive cross-sectional study was conducted on 60,798 workers in the Spanish Mediterranean area on whom different atherogenic indices (cholesterol/HDL, LDL/HDL, triglycerides/HDL) were determined, and the influence they have in the different productive work sectors. Results: In women, the mean values of the different atherogenic indices are better in the health sector, while they are better in men in the primary sector. The percentage of working women with low values is also greater in the healthcare sector, while in men there is no clear predominant sector, with the best values being shown in the hospitality and primary sector. Conclusion: The distribution of cardiovascular risk factors and the values of the different atherogenic indices analyzed vary in different industrial sectors

Desigualdades socioeconómicas y diferencias según sexo y edad en los factores de riesgo cardiovascular / Socioeconomic inequalities and age and gender differences in cardiovascular risk factors

Objetivo: Describir los factores de riesgo cardiovascular en población trabajadora de las Islas Baleares y analizar si las diferencias por clase social varían en función de la edad y el sexo. Métodos: Estudio transversal con una muestra de trabajadores/as activos/as de 20-65 años de edad de las Islas Baleares, incluidos en el estudio durante su revisión laboral periódica del año 2011. Se recogieron las siguientes variables: ocupación, clase social, edad, sexo, talla, peso, tabaquismo, presión arterial, perfil lipídico y glucosa. Se calculó el riesgo cardiovascular según dos ecuaciones (Framingham y REGICOR). Resultados: Se observaron diferencias por clase social en la mayoría de los factores de riesgo cardiovascular. Estas diferencias presentaron un patrón diferencial por grupo de edad y sexo. Las diferencias por clase social para la obesidad en las mujeres aumentaron con la edad, mientras que en los hombres disminuyeron. La hipertensión arterial presentó más diferencias por clase social entre las mujeres que entre los hombres, y en ambos sexos estas diferencias aumentaron con la edad. El perfil lipídico en las mujeres mostró diferencias importantes por clase social, que se acentuaron con la edad, en especial en el caso de bajos valores de colesterol HDL. Conclusiones: Las desigualdades por clase social en los factores riesgo cardiovascular fueron mayores entre las mujeres que entre los hombres. Algunos factores de riesgo cardiovascular, como el tabaquismo y la obesidad, presentan desigualdades importantes en etapas muy tempranas de la vida (AU)

Objective: To describe the cardiovascular risk factors in a working population in the Balearic Islands and to examine whether differences by social class vary according to age and gender. Methods: A cross-sectional study was carried out in a sample of active workers aged 20-65 years in the Balearic Islands. The participants were included in the study during their annual work health assessment in 2011. The following variables were collected: occupation, social class, age, gender, height, weight, smoking, blood pressure, lipid profile, and glucose levels. Cardiovascular risk was calculated using two different equations (Framingham and REGICOR). Results: Differences by social class were observed for most cardiovascular risk factors. The pattern of these differences differed depending on age group and gender. Differences in obesity by social class increased with age in women but decreased in men. More differences in hypertension by social class were found among women than among men, with differences increasing with age in both genders. Significant differences by social class were found among women in lipid profile, and these differences increased with age, mainly for low levels of high-density lipoprotein-cholesterol. Conclusions: Inequalities in cardiovascular risk factors by social class were higher among women than among men. Some cardiovascular risk factors such as smoking and obesity showed significant inequalities from a very early age (AU)

[Socioeconomic inequalities and age and gender differences in cardiovascular risk factors]. / Desigualdades socioeconómicas y diferencias según sexo y edad en los factores de riesgo cardiovascular.

OBJECTIVE: To describe the cardiovascular risk factors in a working population in the Balearic Islands and to examine whether differences by social class vary according to age and gender. METHODS: A cross-sectional study was carried out in a sample of active workers aged 20-65 years in the Balearic Islands. The participants were included in the study during their annual work health assessment in 2011. The following variables were collected: occupation, social class, age, gender, height, weight, smoking, blood pressure, lipid profile, and glucose levels. Cardiovascular risk was calculated using two different equations (Framingham and REGICOR). RESULTS: Differences by social class were observed for most cardiovascular risk factors. The pattern of these differences differed depending on age group and gender. Differences in obesity by social class increased with age in women but decreased in men. More differences in hypertension by social class were found among women than among men, with differences increasing with age in both genders. Significant differences by social class were found among women in lipid profile, and these differences increased with age, mainly for low levels of high-density lipoprotein-cholesterol. CONCLUSIONS: Inequalities in cardiovascular risk factors by social class were higher among women than among men. Some cardiovascular risk factors such as smoking and obesity showed significant inequalities from a very early age.

[Atherogenic indices in workers of different occupational sectors of the Spanish Mediterranean area]. / Índices aterogénicos en trabajadores de diferentes sectores laborales del área Mediterránea Española.

INTRODUCTION: Atherogenic indices predict cardiovascular disease, as they provide a good reflection of the clinical and metabolic interactions of lipid fractions. MATERIAL AND METHOD: A descriptive cross-sectional study was conducted on 60,798 workers in the Spanish Mediterranean area on whom different atherogenic indices (cholesterol/HDL, LDL/HDL, triglycerides/HDL) were determined, and the influence they have in the different productive work sectors. RESULTS: In women, the mean values of the different atherogenic indices are better in the health sector, while they are better in men in the primary sector. The percentage of working women with low values is also greater in the healthcare sector, while in men there is no clear predominant sector, with the best values being shown in the hospitality and primary sector. CONCLUSION: The distribution of cardiovascular risk factors and the values of the different atherogenic indices analyzed vary in different industrial sectors.

Effectiveness of the Heart Age tool for improving modifiable cardiovascular risk factors in a Southern European population: a randomized trial.

AIMS: To test whether communicating cardiovascular diseases (CVD) risk using a novel risk assessment tool (Heart Age) will be able to motivate a population to adopt healthier lifestyles and improve CVD risk profile over the use of a traditional percentage-based tool. METHODS: A single-blind randomized intervention study was carried out in a Caucasian population. A total of 3153 subjects were randomly allocated to one of three study groups: control (conventional medical advice was given to the subjects), Framingham REGICOR (10-year percentage risk score, calibrated to Spanish population was given to the subjects), or Heart Age group (Heart Age tool was administered to the subjects). Anthropometrical and metabolic parameters were measured and lifestyle habits were recorded at recruitment and 12-months post intervention. RESULTS: Both the Framingham REGICOR and the Heart Age intervention groups demonstrated significant decreases in their risk scores at post intervention compared to the control group, with the improvement being of a greater magnitude in the Heart Age group. No differences per gender were observed in the Heart Age group. CONCLUSIONS: Informing patients about their CVD risk expressed as the new Heart Age tool results in a reduction in their CVD risk higher than the one observed when the Framingham REGICOR risk score was used.

La enseñanza de la Medicina del Trabajo en la licenciatura y en el grado de Medicina / Occupational Medicine in the degree of Medicine program

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Body adiposity index and cardiovascular health risk factors in Caucasians: a comparison with the body mass index and others.

BACKGROUND: Several studies have shown a relation between the adipose tissue accumulation and a higher risk for developing metabolic and cardiovascular diseases. Thus, body fat content and, mainly, the fat distribution or adiposity could be considered as important indicators of health risk. In spite of presenting several limitations, BMI is the most widely used and accepted index for classifying overweight and obesity. The aim of the study was to evaluate the correlations between Body Adiposity Index (BAI), BMI and other adiposity indexes such as WC, WHR and WHtR with cardiovascular and metabolic risk factors. Furthermore, the behavior of BAI and BMI regarding the ability to discriminate overweight or obese individuals was also analyzed. RESEARCH METHODOLOGY/PRINCIPAL FINDINGS: A cross-sectional study was conducted in Spanish Caucasian adult workers. Participants in the study (29.214 men and 21.040 women, aged 20-68 years) were systematically selected during their work health periodic examinations. BAI, BMI, WHR, WHtR, body weight, hip and waist circumference (WC) as well as systolic and diastolic blood pressure were measured. Serum levels of high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C), triglycerides (TG) and glucose were also determined. Results of the study indicated that BAI was less correlated with cardiovascular risk factors and metabolic risk factors than other adiposity indexes (BMI, WC and WHtR). The best correlations were found for WHtR. In addition, the BAI presented lower discriminatory capacity than BMI for diagnosing metabolic syndrome (MS) using both IDF and ATP III criteria. A different behavior of the BAI in men and women when considering the ability to discriminate overweight or obese individuals was also observed. CONCLUSIONS: The adiposity indexes that include the waist circumference (WHtR and WC) may be better candidates than BAI and BMI to evaluate metabolic and cardiovascular risk in both clinical practice and research.

[Prevalence of cardiovascular risk factors in Balearic workers apparently healthy]. / Prevalencia de factores de riesgo cardiovascular en trabajadores aparentemente sanos.

BACKGROUND: the prevalence of cardiovascular risk factors is well known in the general population. The aim of our study is to determine the prevalence of unknown major cardiovascular risk factors, in an apparently healthy Balearic working population. METHOD: data were obtained to 3,035 people randomly selected and with unknown previous diagnosis of hypertension, diabetes or hypercholesterolemia. To compare proportions we used the χ2 test and the t-Student test for comparison of means. RESULTS: the prevalence of unknown hypertension in men was 20.6%, hypercholesterolemia 11.6%and 2.6% diabetes. The prevalence of unknown hypertension, hypercholesterolemia and diabetes in women were 8.3,5.4 and 0.8%, respectively. All cardiovascular risk factors except low HDL-cholesterol were more prevalent in men. 14.4%of men and 5.5% of women met metabolic syndrome. CONCLUSIONS: there is a very high prevalence of cardiovascular risk factors in the working population considered theoretically healthy. This highlights the important role in this field from the occupational health units to make them emerge.

Profilaxis antirretroviral en una trabajadora hospitalaria gestante / Antiretroviral prophylaxis in a pregnant hospital worker

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