Assuntos
Protocolos de Quimioterapia Combinada Antineoplásica/uso terapêutico , Melanoma/tratamento farmacológico , Proteínas Proto-Oncogênicas B-raf/antagonistas & inibidores , Neoplasias Cutâneas/tratamento farmacológico , Axila , Dermoscopia , Feminino , Humanos , Indóis/administração & dosagem , Metástase Linfática , Melanoma/patologia , Microscopia Confocal , Pessoa de Meia-Idade , Quinases de Proteína Quinase Ativadas por Mitógeno/antagonistas & inibidores , Neoplasias Cutâneas/patologia , Sulfonamidas/administração & dosagem , Resultado do Tratamento , VemurafenibRESUMO
The cases of two patients with linear, cordlike lesions on the anterolateral chest wall are reported. Both cases suggested a clinical diagnosis of Mondor's disease (i.e., sclerosing periphlebitis of the chest wall) with atypical aspects. The histologic picture showed a diffuse dermal infiltrate, predominantly of eosinophils mixed with lymphocytes and histiocytes, with some evidence of collagen degeneration. No flame figures were seen. Problems of differential diagnosis are discussed.
Assuntos
Flebite/patologia , Pele/irrigação sanguínea , Axila , Eosinofilia/patologia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Pele/patologia , Tórax , Veias/patologiaRESUMO
A case of unilateral linear basal cell nevus, diffuse osteoma cutis, unilateral anodontia, and abnormal bone mineralization is reported. Unlike the anodontia, the unilateral linear basal cell nevus and osteoma cutis began to appear in adulthood. A hamartomatous process is suggested to explain these conditions. This complex syndrome has not been reported in the literature.
Assuntos
Doenças Ósseas Metabólicas/complicações , Síndrome do Hamartoma Múltiplo/patologia , Minerais/metabolismo , Neoplasias Primárias Múltiplas/patologia , Neoplasias Cutâneas/patologia , Idoso , Anodontia/complicações , Síndrome do Nevo Basocelular/complicações , Síndrome do Nevo Basocelular/patologia , Síndrome do Hamartoma Múltiplo/complicações , Humanos , Masculino , Osteoma/complicações , Osteoma/patologia , Neoplasias Cutâneas/complicaçõesRESUMO
17 cases of epidermoid cysts with vellus hairs in their lumen are reported. The clinical diagnosis was usually cysts. In 12 cases the lesions were solitary and in 5 they were multiple, small and closely set. Microscopically, the findings of the wall were those of the epidermoid cyst containing in their lumen hair shafts of lanugo size. The solitary variety of these cysts can be considered as the solitary counterpart of the eruptive vellus hair cyst. Problems of differential diagnosis are discussed.
