Esophageal intramural pseudodiverticulosis with esophageal cancer improved by target rotation irradiation: case report.

Etiology of esophageal intramural pseudodiverticulosis is still unknown but several accompanying diseases have been reported, for example, reflux esophagitis, esophageal cancer, diabetes mellitus and so on. We have experienced a case of esophageal intramural pseudodiverticulosis with cancer improved by radiation therapy. In this case, there were esophageal cancer in the cervical esophagus, with intramural spreading in whole esophagus. This case was delivered irradiation to the entire esophagus by target rotation method. After irradiation, intramural pseudodiverticula, intramural spreading and primary site of esophageal cancer were improved. This is an interest case report that esophageal intramural pseudodiverticula with cancer was disappeared by radiation therapy.

[Applicability of the dual interval echo train (DIET) method for female pelvic diseases].

Dual interval echo train fast SE (DIET-FSE) is a modified fast SE technique. It attenuates fat signals by applying a time interval between an excitation pulse and the first echo, which is the odd-number of the following echo interval, and by decreasing the number of high frequency refocusing pulses before collecting echoes in the center of the k space, which determines the contrast. Unlike many other fat-suppression methods, this technique is less affected by susceptibility effects. In this study, we compared DIET-FSE with FSE and conventional SE of the female pelvis. The results of DIET-FSE showed a stable, obvious fat suppression effect which resulted in the easy detection of pelvic organs such as the intestines and ovaries, as compared with FSE. The reductions in imaging time and motion artifacts also permitted more precise differentiation between the normal pelvic organs and lesions than conventional T2-weighted SE. These results imply that the DIET-FSE is useful for the diagnosis of female pelvic disorders.

[Blood leukotriene B4 response to endotoxin in fish oil fed rats].

Six-week-old male Wistar rats were given a low fat diet containing 15% cod liver oil (FO; n = 30) or 15% safflower oil (SO; n = 30) for 6 weeks. In the polymorphonuclear leukocytes, arachidonic acid (AA) was significantly lower in the FO group than in the SO group (p < 0.001), and eicosapentaenoic acid (EPA) in the FO group was present in large amounts showing the EPA/AA ratio of 1.76. When lipopolysaccharide (LPS; 10mg/kg) was intraperitoneally injected, white blood cell counts in the blood significantly decreased in both groups (p < 0.001) compared to the controls 2 hours later, and at 4 hours, the counts in the SO group (2,033 +/- 151/mm3) were lower than in the FO group (3,189 +/- 624/mm3), (p < 0.01). In both groups, leukotriene B4 (LTB4) in the whole blood increased at 4 hours following LPS-administration compared to the controls (1,219 +/- 167.3pg/ml in the SO group and 600.0 +/- 109.0pg/ml in the FO group, p < 0.001). It should be noted that the level of LTB4 in the SO group was significantly higher than in the FO group (p < 0.001). Changes of the metabolites including decreased LTB4 production in the arachidonic cascade related to the increase of EPA may play a role in the inhibition of the decrease in white blood cell counts.

Adenomyomatosis of the gallbladder: a clinical survey of 30 surgically treated patients.

Thirty patients with adenomyomatosis of the gallbladder (AMG) were operated on between January 1983 and June 1990. They were made up 3.3% of patients who underwent cholecystectomy during the same interval. Of the 30 patients, ages ranged from 22 to 77 years (mean 52.3 years) and the male-to-female ratio was 8:7. Among the macroscopic types, 10 cases of generalized, 12 of segmental (S) and 8 of fundal (F) were noted, and the size of the affected portion in type S (0.8 +/- 0.2 cm, mean +/- SD) was significantly thinner than in other two types (p less than 0.05). Although the main symptom was abdominal pain, the majority of patients with type F had no complaints. Twenty patients (27%) were accompanied by gallstones including cholesterol stones in 60% of cases, and all six cases showing microbes in the bile had gallstones. Only six patients were diagnosed as AMG by preoperative imaging techniques. Other diagnoses comprised 15 of chronic cholecystitis and 3 of suspected gallbladder carcinoma. To identify the expanded Rokitansky-Aschoff sinuses, endoscopic retrograde cholangiography and/or ultrasonography of the abdomen were most useful. No preponderant coexistent lesion other than gallstones was noted. Levels of carcinoembryonic antigen in gallbladder bile in cases of AMG (2.5 +/- 1.5 ng/ml, mean +/- SD) were significantly lower than in gallbladder carcinoma (p less than 0.01). All the patients were easily treated with cholecystectomy, and 24 patients who have been followed up after surgery are doing well.(ABSTRACT TRUNCATED AT 250 WORDS)