Physical Activity and Survival among Long-term Cancer Survivor and Non-Cancer Cohorts.

Evidence suggests physical activity improves prognosis following cancer diagnosis; however, evidence regarding prognosis in long-term survivors of cancer is scarce. We assessed physical activity in 1,589 cancer survivors at an average 8.8 years following their initial diagnosis and calculated their future mortality risk following physical activity assessment. We also selected a cancer-free cohort of 3,145 age, sex, and survey year group-matched cancer-free individuals from the same source population for comparison purposes. Risks for cancer-specific mortality and all-cause mortality in relation to physical activity levels were estimated using Cox regression proportional hazard regression analyses within the cancer and non-cancer cohorts. Physical activity levels of 360+ min per week were inversely associated with cancer-specific mortality in long-term cancer survivors [hazard ratios (HR) = 0.30 (95% confidence intervals (CI) 0.13-0.70)] and participants without prior cancer [HR = 0.16 (95% CI 0.05-0.56)] compared with no reported physical activity. Physical activity levels of 150-359 and 360+ min were inversely associated with all-cause mortality in long-term cancer survivors [150-359 min; HR = 0.55 (95% CI 0.31-0.97), 360+ min; HR = 0.41 (95% CI 0.21-0.79)] and those without prior cancer [150-359 min; HR = 0.52 (95% CI 0.32-0.86), 360+ min; HR = 0.50 (95% CI 0.29-0.88)]. These results suggest that meeting exercise guidelines of 150 min of physical activity per week were associated with reduced all-cause mortality in both long-term cancer surviving and cancer-free cohorts. Exceeding exercise oncology guidelines (360+ min per week) may provide additional protection in terms of cancer-specific death.

Parents' perception of their child's weight status and intention to intervene: a Western Australian cross-sectional population survey, 2009-12.

OBJECTIVE: To report on parents' perceptions of their child's weight status and how the child's body mass index (BMI) is associated with parent intentions to change or maintain the child's weight. METHODS: Estimates were derived via data collected from 4,437 parents from 2009 to 2012 as part of the Western Australian Health and Wellbeing Surveillance System. To measure weight perceptions, parents were asked, "Is your child underweight, normal weight, overweight or very overweight?" BMI values were also derived via parent-reported height and weight. Parent intentions were assessed by asking parents, "What are your intentions regarding your child's weight?" RESULTS: Significantly fewer parents perceived their child as overweight (8.2%) or very overweight (0.2%) than was derived via parent-reported height and weight (16.3% and 5.8%, respectively). More than half the parents with children above or below the healthy BMI range reported an intention to "do nothing" about their child's weight (between 54.5% and 70.0%). CONCLUSIONS: A large proportion of Western Australian parents misjudge their child's weight status and the majority express no intention to help their child achieve a healthy weight. IMPLICATIONS: The results reinforce the importance of population-level, parent-focussed interventions targeting perceptions of children's weight and appropriate action.

Adult preferences for influenza vaccines with lower likelihood of side effects.

BACKGROUND: Concerns about possible side effects are a well-recognized barrier to influenza vaccination and emerging data indicate rates of reactogenicity for inactivated influenza vaccines may vary by manufacturer. We surveyed adults to assess their preference for hypothetical influenza vaccines with equivalent efficacy but differing rates of serious and minor adverse events. RESULTS: The response rate was 94% (1006/1071); 44% of respondents reported receiving influenza vaccine at least once in the past. Seventy-two percent of respondents expressed a preference for vaccines that provided the same level of protection, but were less likely to produce serious side effects, and 55% expressed a preference for vaccines less likely to produce minor side effects. No significant differences by prior influenza vaccination history, age group or gender were identified. CONCLUSIONS: A substantive proportion of adults have a strong preference for influenza vaccine formulations less likely to produce even minor side-effects, such as injection site reactions. Identifying influenza vaccines with equivalent efficacy but lower reactogenicity is important because experience with side effects may negatively impact future vaccine uptake. METHODS: Computer assisted telephone interviews were conducted as part of a population-based survey using a stratified random sample drawn from the residential White Pages® telephone directory.

Lifestyle factors, medication use and risk for ischaemic heart disease hospitalisation: a longitudinal population-based study.

BACKGROUND: Lifestyle factors have been implicated in ischaemic heart disease (IHD) development however a limited number of longitudinal studies report results stratified by cardio-protective medication use. PURPOSE: This study investigated the influence of self-reported lifestyle factors on hospitalisation for IHD, stratified by blood pressure and/or lipid-lowering therapy. METHODS: A population-based cohort of 14,890 participants aged 45+ years and IHD-free was identified from the Western Australian Health and wellbeing Surveillance System (2004 to 2010 inclusive), and linked with hospital administrative data. Adjusted hazard ratios for future IHD-hospitalisation were estimated using Cox regression. RESULTS: Current smokers remained at higher risk for IHD-hospitalisation (adjusted HR=1.57; 95% CI: 1.22-2.03) after adjustment for medication use, as did those considered overweight (BMI=25-29 kg/m(2); adjusted HR=1.28; 95% CI: 1.04-1.57) or obese (BMI of ≥30 kg/m(2); adjusted HR=1.31; 95% CI: 1.03-1.66). Weekly leisure-time physical activity (LTPA) of 150 minutes or more and daily intake of 3 or more fruit/vegetable servings reduced risk by 21% (95% CI: 0.64-0.97) and 26% (95% CI: 0.58-0.96) respectively. Benefits of LTPA appeared greatest in those on blood pressure lowering medication (adjusted HR=0.50; 95% CI: 0.31-0.82 [for LTPA<150 mins], adjusted HR=0.64; 95% CI: 0.42-0.96 [for LTPA>=150 mins]). IHD risk in smokers was most pronounced in those taking neither medication (adjusted HR=2.00; 95% CI: 1.41-2.83). CONCLUSION: This study confirms the contribution of previously reported lifestyle factors towards IHD hospitalisation, even after adjustment for antihypertensive and lipid-lowering medication use. Medication stratified results suggest that IHD risks related to LTPA and smoking may differ according to medication use.

Predictors of uptake of influenza vaccination--a survey of pregnant women in Western Australia.

BACKGROUND: Pregnant women are at increased risk of complications following influenza infection. Vaccination is the most effective preventive strategy. This survey aimed to determine the levels of uptake of influenza vaccine in pregnant women in Western Australia (WA), the proportion of women offered vaccination as part of antenatal care, and women's attitudes toward influenza vaccination in pregnancy. METHODS: Computer assisted telephone interviews were conducted with 416 randomly selected women who were pregnant during the 2012 influenza vaccination season. RESULTS: Influenza vaccination coverage was 23%. Predictors of vaccination included believing that vaccination is safe for the infant, having been recommended vaccination by an antenatal care provider, and attending a general practitioner for most antenatal care. The majority (74%) of unvaccinated women reported that they would have the vaccine if their antenatal care provider recommended it. DISCUSSION: General practitioners lead the way in antenatal influenza vaccination in WA. Vaccination coverage can be improved if recommending and offering influenza vaccination becomes a routine part of antenatal care.