Osteoclast-Forming Suppressive Compounds from Anoectochilus formosanus / 日本補完代替医療学会誌

<i>Anoectochilus formosanus</i>, an orchidaceous plant native to Taiwan, is widely used as a folk medicine in Taiwan and other Southeast Asian countries. We attempted to isolate the bioactive principles from <i>A. formosanus</i> and succeeded in purifying the compounds. Two known compounds (<i>N</i>-<i>cis</i>-feruloyl tyramine and <i>N</i>-<i>trans</i>-feruloyl tyramine) were isolated and both significantly inhibited osteoclast formation, which is important in the development of osteoporosis.<br>