RESUMO
An epizootic of ulcerative to nodular ventral dermatitis was observed in a large breeding colony of 8-month to 5-year-old leopard geckos (Eublepharis macularius) of both sexes. Two representative mature male geckos were euthanized for diagnostic necropsy. The Chrysosporium anamorph of Nannizziopsis vriesii (CANV) was isolated from the skin lesions, and identification was confirmed by sequencing of the internal transcribed spacer region of the rRNA gene. Histopathology revealed multifocal to coalescing dermal and subcutaneous heterophilic granulomas that contained septate fungal hyphae. There was also multifocal epidermal hyperplasia with hyperkeratosis, and similar hyphae were present within the stratum corneum, occasionally with terminal chains of arthroconidia consistent with the CANV. In one case, there was focal extension of granulomatous inflammation into the underlying masseter muscle. This is the first report of dermatitis and cellulitis due to the CANV in leopard geckos.
Assuntos
Celulite (Flegmão)/veterinária , Chrysosporium/isolamento & purificação , Dermatite/veterinária , Dermatomicoses/veterinária , Granuloma/veterinária , Lagartos/microbiologia , Animais , Celulite (Flegmão)/microbiologia , Celulite (Flegmão)/patologia , Chrysosporium/genética , DNA Fúngico/química , DNA Fúngico/genética , DNA Espaçador Ribossômico/química , DNA Espaçador Ribossômico/genética , Dermatite/microbiologia , Dermatite/patologia , Dermatomicoses/microbiologia , Dermatomicoses/patologia , Feminino , Granuloma/microbiologia , Granuloma/patologia , Hiperplasia/veterinária , Hifas , Masculino , Dados de Sequência Molecular , Pele/microbiologia , Pele/patologia , Úlcera Cutânea/microbiologia , Úlcera Cutânea/patologia , Úlcera Cutânea/veterinária , Esporos FúngicosRESUMO
This multi-institutional report describes 8 cases of rhabdomyosarcoma in horses. Four neoplasms were in the tongue and other areas of the mouth or head, 2 were in the abdominal wall, and 1 each was in right shoulder muscles and heart. Four rhabdomyosarcomas that were less than 10 cm in diameter were treated by surgical excision or radiation with no recurrence. Two neoplasms greater than 10 cm in diameter in the abdominal wall and the right shoulder were considered inoperable and led to decisions to euthanize the horses. Two neoplasms were incidental findings at necropsy. All the neoplasms were classified as embryonal except for 1 pleomorphic rhabdomyosarcoma. These 8 cases were evaluated with 9 published case reports of equine rhabdomyosarcoma. For all cases, the most common sites were limb muscles (5/17) and tongue (4/17). Metastasis was reported in 4 of the previously published cases; none was found in this study.
