Positron Emission Tomography Findings in Atypical Polypoid Adenomyoma.

Atypical polypoid adenomyoma (APAM) is a rare polypoid tumor of the uterus composed of atypical endometrial glands surrounded by smooth muscle. A 29-year-old nulligravida, was clinically diagnosed with endocervical myoma and underwent trans-uterine cervical resection with hysteroscope. The histopathological diagnosis of specimens was APAM. Eight months later, she diagnosed recurrent uterine tumor. The positron emission tomography (PET-CT) imaging showed an increased fluorodeoxyglucose uptake. She has performed hysterectomy and was diagnosed APAM. Therapy for APAM depends on multiple factors such as age at presentation and desire for childbearing among others. This is the first report of PET-CT findings in APAM.

Adult pancreatic hemangioma: A case report.

Vascular neoplasms of the pancreas are extremely rare and usually manifest as symptomatic, cystic lesions. This study presents a case that includes the clinicopathologic information used to discriminate pancreatic hemangioma from other types of cystic lesion of the pancreas. A 40-year-old female visited hospital with a chief complaint of abdominal pain. The serum CEA and CA19-9 levels of the patient were within the normal limits. An abdominal computed tomography scan and magnetic resonance imaging showed a 100-mm mass lesion in the body and tail of the pancreas, and the tumor extended toward the retroperitoneum and surrounded the splenic vein. The lesion was subsequently resected. Macroscopically, it was a multiloculated cyst with intracystic hemorrhage. Microscopically, the lesion was composed of numerous, heterogeneous cysts lined by a flattened single layer of cells without significant atypia. Notably, numerous neoplastic vessels extended into the interlobular septa of the pancreas and surrounded the main pancreatic duct. Immunohistochemical analysis showed that the lining cells expressed CD31 and CD34. The lesion was diagnosed as adult pancreatic hemangioma. Surgical treatment may be required when a direct contact between the lesion and the pancreatic tissue is demonstrated using imaging.

Squamous cell carcinoma with apocrine features of the breast: A case report.

A rare case of squamous cell carcinoma (SCC) with apocrine features was investigated; the focus was on the histological characteristics of the cancer cells in a 68-year-old female exhibiting an ulcerated lesion of the right breast. Diagnostic imaging methods identified a lobulated solid tumor and indicated multiple enlarged lymph nodes in the left axilla, which confirmed the diagnosis of advanced breast cancer; thus, a mastectomy was performed. Macroscopic investigations identified the tumor as a white, solid lesion measuring 66 × 68 × 47 mm, which exhibited necrosis. Histologically, the tumor was predominantly solid and exhibited nest patterns, in addition to intracellular keratinization. Immunohistochemical staining identified the tumor cells as positive for cytokeratin 5/6, 34ßE12 and P63. The lesion was considered to be an SCC demonstrating negative expression for the human epidermal growth factor receptor 2, estrogen receptor and progesterone receptor; therefore, the tumor was a triple-negative breast cancer. Conversely, approximately one-third of the tumor cells indicated abundant eosinophilic cytoplasm and gross cystic disease fluid, which was demonstrated via protein-15 staining; this indicated the presence of apocrine features. In addition, the androgen receptor was expressed in the tumor cells, thus the lesion was diagnosed as an SCC of the breast, exhibiting apocrine features.

Malignant melanoma arising in a plaque-type blue nevus.

Blue nevus is a type of dermal melanocytosis and has a variety of clinicopathological characteristics. A few particular variants are generally accepted as discrete clinicopathological entities. Plaque-type blue nevus (PTBN) is one of the variants of blue nevus. PTBN presents at birth or arises in early childhood, and shows a combination of features found in common blue nevus and cellular blue nevus. In this report, we describe a malignant melanoma arising in association with a PTBN in a 65-year-old male. The tumor appeared as a well circumscribed but partially infiltrative upper-abdominal mass, and was heavily pigmented and consisted of a spindle or epithelioid highly cellular component with mitotic figures and tumor necroses. In the skin around the tumor, multiple pigmented lesions were scattered around the trunk, and these had been recognized since childhood. Histologically, skin lesions showed sparse and wide distribution of the dendritic melanocytes with dense melanin pigments and melanophages between the collagen bundles from the reticular dermis to the abdominal skeletal muscle. We also discuss the histological features and clinical course in our patient in context with previous related literature.

MRI of clear cell hidradenoma.

Clear cell hidradenoma is a rare benign skin appendageal tumor whose imaging findings have been even more rarely reported. We experienced a large clear cell hidradenoma of the left elbow in a 22-year-old man. MRI revealed a complex solid and cystic appearance with enhancing solid component.