[Pathogenesis of diffuse fecal peritonitis]. / O patogeneze razlitogo kalovogo peritonita.

Mongrel albino rats were given intraperitoneal injections of blue pus bacillus endotoxin and human, rat, and guinea-pig fetal suspensions. Analysis of central and peripheral hemodynamics and the indices of the blood coagulation system showed that the severity of the animals' condition was determined by the degree of peripheral hemodynamic disorders associated with changes of the blood rheologic properties. Control of the presence of bacteremia in peritonitis showed that it is encountered both in severe intoxication (injection of human fecal suspension) and in a relatively favourable process (injection of rat fecal suspension). The shifts in the blood coagulation system were characterized by marked individual variability.

[Control of anticoagulant therapy by using soluble thromboplastin]. / Kontro'l antikoaguliantnoi terapii pri pomoshchi preparata "tromboplastin rastvorimyi".

The characteristics of soluble thromboplastin, a new coagulant agent, were under study. This drug is a high-molecular lipoprotein complex of human cadaver brain, purified by gel chromatography. The new preparation has been standardized and compared to thromboplastin preparations manufactured in this country and abroad. Soluble thromboplastin has been found fairly sensitive to reductions of the prothrombin factors levels, it may be used for monitoring the efficacy of indirect anticoagulant therapy, and conforms to WHO regulations for thromboplastin reference agents; this latter fact recommends this new drug as a thromboplastin reference agent in this country.