[Preliminary experience in an intensive care unit with Impella Recover. A new circulatory support system in patients with low cardiac output]. / Experiencia preliminar en una unidad de cuidados intensivos con Impella Recover. Asistencia ventricular microaxial en pacientes con bajo gasto cardíaco.

The low cardiac output syndrome following cardiopulmonary bypass is characterized by poor left ventricular contractibility that requires the support of high doses of vasoactive drugs, intra-aortic balloon pump, and sometimes makes it impossible to disconnect the extracorporeal circulation. We report 5 cases in which a "recently created" device in left ventricular support was inserted, the Impella Recover (Impella CardioSystems AG, Aachen, Germany) due to cardiogenic shock at the end of the surgery. Four of these patients recovered their heart function and the ventricular support could be removed after 70+/-55 h. In a fifth patient, the right ventricular failure warranted the use of Berlin Heart assist device.

QRS duration and early hemodynamic instability after coronary revascularization surgery.

INTRODUCTION AND OBJECTIVES: The duration of the QRS interval measured by ECG is a marker of ventricular dysfunction and indicates a poor prognosis. Its value in patients undergoing coronary revascularization surgery has not been established. METHODS: The study involved 203 consecutive patients (age 64+/-9 years, 74% male) scheduled for elective coronary surgery. The maximum QRS duration measured on a preoperative 12-lead ECG was recorded. Hemodynamic instability was defined as the occurrence of cardiac death, heart failure, or a need for intravenous inotropic drugs or intra-aortic balloon counterpulsation during the postoperative period. RESULTS: The occurrence of hemodynamic instability (n=94, 46%) was associated with a longer preoperative QRS duration (97.5+/-21.14 ms vs 88.5+/-16.9 ms; P=.001). The QRS duration was also longer in patients who developed heart failure (n=23; 104.3+/-22.9 ms vs. 91.1+/-18.5 ms; P=.002), needed inotropic drugs (n=77; 96.5+/-20.5 ms vs. 90.1+/-18.2 ms; P=.007) or developed postoperative atrial fibrillation (n=58; 98.2+/-23.8 ms vs. 90.4+/-17.0 ms; P=.018). Bundle branch block was associated with a greater need for intra-aortic balloon counterpulsation (29% vs 12%; P=.012) or inotropic drugs (58% vs 35%; P=.014) and a higher incidence of hemodynamic instability (69% vs 42%; P=.006). Multivariate analysis identified the following independent predictors of hemodynamic instability: QRS duration (adjusted odds ratio [OR] per 10 ms=1.49; 95% confidence interval [CI], 1.11-2; P=.007), the lack of an arterial graft (OR=3.6; 95% CI, 1.14-11.6; P=.029) and extracorporeal circulation time (OR per min=1.013; 95% CI, 1.003-1.023; P=.013). CONCLUSIONS: The intraventricular conduction delay, or QRS duration, was associated with a higher risk of postoperative hemodynamic instability following coronary surgery.

Duración del QRS y deterioro hemodinámico precoz tras cirugía de revascularización coronaria / QRS Duration and Early Hemodynamic instability after coronary Revascularization Surgery

Introducción y objetivos. La duración del intervalo QRS en el ECG es un marcador de disfunción ventricular y peor pronóstico. Su valor en pacientes sometidos a cirugía de revascularización coronaria no ha sido establecido. Métodos. Estudiamos a 203 pacientes consecutivos (64 ± 9 años de edad; el 74% varones) programados para cirugía electiva coronaria. Se registró la duración máxima del intervalo QRS en el ECG de 12 derivaciones preoperatorio. Definimos inestabilidad hemodinámica como la aparición de muerte cardiaca, insuficiencia cardiaca, uso de fármacos inotrópicos intravenosos o balón de contrapulsación intraaórtico durante el postoperatorio. Resultados. La aparición de inestabilidad hemodinámica (n = 94 [46%]) se asoció a una mayor duración del intervalo QRS preoperatorio (97,5 ± 21,14 frente a 88,5 ± 16,9 ms; p = 0,001). El QRS fue mayor en quienes apareció insuficiencia cardiaca (n = 23; 104,3 ± 22,9 frente a 91,1 ± 18,5 ms; p = 0,002), precisaron inotrópicos intravenosos (n = 77; 96,5 ± 20,5 frente a 90,1 ± 18,2 ms; p = 0,007) o sufrieron fibrilación auricular postoperatoria (n = 58; 98,2 ± 23,8 frente a 90,4 ± 17 ms; p = 0,018). El bloqueo de rama se asoció a mayor necesidad de balón de contrapulsación (el 29 frente al 12%; p = 0,012), inotrópicos (el 58 frente al 35%; p = 0,014) y mayor incidencia de inestabilidad hemodinámica (el 69 frente al 42%; p = 0,006). Tras el ajuste multivariable, los predictores de inestabilidad hemodinámica fueron la duración del QRS (odds ratio [OR] = 1,49; intervalo de confianza [IC] del 95%, 1,11-2; p = 0,007), la ausencia de injerto arterial (OR = 3,6; IC del 95%, 1,14-11,6; p = 0,029) y el tiempo de circulación extracorpórea (OR = 1,013; IC del 95%, 1,003-1,023; p = 0,013), con independencia de otros factores de riesgo. Conclusiones. El retraso de la conducción intraventricular o duración del intervalo QRS se asocia a mayor riesgo de inestabilidad hemodinámica durante el post-operatorio de cirugía coronaria (AU)

Introduction and objectives. The duration of the QRS interval measured by ECG is a marker of ventricular dysfunction and indicates a poor prognosis. Its value in patients undergoing coronary revascularization surgery has not been established.Methods. The study involved 203 consecutive patients (age 64±9 years, 74% male) scheduled for elective coronary surgery. The maximum QRS duration measured on a preoperative 12-lead ECG was recorded. Hemodynamic instability was defined as the occurrence of cardiac death, heart failure, or a need for intravenous inotropic drugs or intra-aortic balloon counterpulsation during the postoperative period.Results. The occurrence of hemodynamic instability (n=94, 46%) was associated with a longer preoperative QRS duration (97.5±21.14 ms vs 88.5±16.9 ms; P=.001). The QRS duration was also longer in patients who developed heart failure (n=23; 104.3±22.9 ms vs. 91.1±18.5 ms; P=.002), needed inotropic drugs (n=77; 96.5±20.5 ms vs. 90.1±18.2 ms; P=.007) or developed postoperative atrial (..) (AU)

Experiencia preliminar en una unidad de cuidados intensivos con Impella Recover®. Asistencia ventricular microaxial en pacientes con bajo gasto cardíaco / Preliminary experience in an intensive care unit with Impella Recover®. A new circulatory support system in patients with low cardiac output

El síndrome de bajo gasto cardíaco tras cardiotomía se caracteriza por una mala contractilidad ventricular izquierda que requiere el apoyo de altas dosis de fármacos vasoactivos, el uso de balón de contrapulsación y en ocasiones imposibilita la desconexión de la circulación extracorpórea. Presentamos 5 casos en los que se implantó un dispositivo de «reciente creación» en la asistencia ventricular izquierda: Impella Recover® (Impella CardioSystems AG, Aachen, Alemania), por shock cardiogénico al final de la intervención. De estos pacientes, 4 recuperaron la función cardíaca y la asistencia ventricular se pudo retirar tras un promedio de 70 ± 55h. En el quinto paciente, el dispositivo no mostró un resultado favorable y se evidenció insuficiencia ventricular derecha, por lo que fue necesario recurrir a una asistencia biventricular tipo Berlin Heart (AU)

The low cardiac output syndrome following cardiopulmonary bypass is characterized by poor left ventricular contractibility that requires the support of high doses of vasoactive drugs, intra-aortic balloon pump, and sometimes makes it impossible to disconnect the extracorporeal circulation. We report 5 cases in which a «recently created» device in left ventricular support was inserted, the Impella Recover® (Impella CardioSystems AG, Aachen, Germany) due to cardiogenic shock at the end of the surgery. Four of these patients recovered their heart function and the ventricular support could be removed after 70 ± 55h. In a fifth patient, the right ventricular failure warranted the use of Berlin Heart assist device (AU)