Circadian parameter as a possible indicator of gait performance and daily activity levels in chronic stroke survivors.

Stroke recovery is a critical public health problem. It involves cognitive and physical impairments leading to physical inactivity. In addition, there are also sleep problems and disruption of the circadian rhythm. In this paper, we analyze the relation between cognitive impairments level, walking performance, sleep and circadian parameters of a group of chronic stroke survivors. Five stroke survivors enrolled in the study. The clinical assessments were: cognitive function (MoCA), the 10 meter-walking test (10MWT), and the 6 minutes walking test (6MWT). The circadian rhythm parameters were obtained for at least one week wearing the actimeters. There was a positive correlation between the duration of the main sleep episode and the MoCA scores. There were significant correlations between the 10MWT and 6MWT and the circadian parameters that were positive for most active period (M10), Interdaily stability (IS), Mesor and Amplitude and negative for intradaily variability (IV). Our results indicate that gait speed and resistance are correlated to circadian rhythm synchronization, lower rhythm variability and more defined activity-rest episodes. This preliminary study underscores the importance of including a continuous measure of sleep and activity cycles in the assessment of stroke survivors.

Feasibility, safety and outcomes of playing Kinect Adventures!™ for people with Parkinson's disease: a pilot study.

OBJECTIVES: To assess the feasibility, safety and outcomes of playing Microsoft Kinect Adventures™ for people with Parkinson's disease in order to guide the design of a randomised clinical trial. DESIGN: Single-group, blinded trial. SETTING: Rehabilitation Center of São Camilo University, Brazil. PARTICIPANTS: Seven patients (six males, one female) with Parkinson's disease (Hoehn and Yahr Stages 2 and 3). INTERVENTIONS: Fourteen 60-minute sessions, three times per week, playing four games of Kinect Adventures! MAIN OUTCOME MEASURES: The feasibility and safety outcomes were patients' game performance and adverse events, respectively. The clinical outcomes were the 6-minute walk test, Balance Evaluation System Test, Dynamic Gait Index and Parkinson's Disease Questionnaire (PDQ-39). RESULTS: Patients' scores for the four games showed improvement. The mean [standard deviation (SD)] scores in the first and last sessions of the Space Pop game were 151 (36) and 198 (29), respectively [mean (SD) difference 47 (7), 95% confidence interval 15 to 79]. There were no adverse events. Improvements were also seen in the 6-minute walk test, Balance Evaluation System Test, Dynamic Gait Index and PDQ-39 following training. CONCLUSION: Kinect-based training was safe and feasible for people with Parkinson's disease (Hoehn and Yahr Stages 2 and 3). Patients improved their scores for all four games. No serious adverse events occurred during training with Kinect Adventures!, which promoted improvement in activities (balance and gait), body functions (cardiopulmonary aptitude) and participation (quality of life).