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1.
J Acoust Soc Am ; 153(5): 3036, 2023 May 01.
Artigo em Inglês | MEDLINE | ID: mdl-37219495

RESUMO

This article is a discussion on the necessity of the assumption of diffuse field in statistical energy analysis and the validity of the coupling power proportionality which states that the vibrational power exchanged between coupled subsystems is proportional to the difference of their modal energies. It is proposed to re-formulate the coupling power proportionality in terms of local energy density instead of modal energy. We show that this generalized form remains valid even if the vibrational field is not diffuse. Three causes of lack of diffuseness have been studied: coherence of rays in symmetrical geometries, nonergodic geometries, and the effect of high damping. Numerical simulations and experimental results conducted on flat plates in flexural vibration are provided to support these statements.

2.
Equine Vet J ; 51(1): 131-135, 2019 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-29758109

RESUMO

BACKGROUND: Laminitis has a considerable impact on the equine industry. Endocrinopathic laminitis is the most common form and affected horses often have hyperinsulinaemia due to an underlying metabolic disorder. OBJECTIVES: The aim of this study was to determine if insulin weakens the structural integrity of digital lamellae and to develop an ex vivo model for the study of hyperinsulinaemia-induced lamellar failure. STUDY DESIGN: Ex vivo experiment. METHODS: Biomechanical testing was used to assess the structural integrity of lamellar explants exposed to either medium alone (control) or medium supplemented with insulin. Lamellar explants comprised of hoof wall, lamellar tissue and distal phalanx were harvested from four adult horses with no evidence of inflammatory disease or pre-existing disease of the digit. Following an equilibration period, explants were incubated in medium or medium supplemented with insulin (2.5 µg/ml) for 8 h prior to biomechanical testing to obtain load (N), stress (MPa), elongation to failure (mm), and Young's modulus (MPa) for each explant. Significant differences were assessed using a mixed linear model with horses as a random factor and control or insulin-treated group as a fixed factor. RESULTS: Lamellar explants incubated in medium supplemented with insulin failed at significantly lower load (P = 0.0001) and lower stress (P = 0.001) and had greater elongation to failure (P = 0.02). MAIN LIMITATIONS: In addition to the ex vivo nature of the study, location-dependent variability in explant structural integrity and variable diffusion of nutrients due to explant size may have been limitations. However, the study design attempted to account for these limitations through random assignment of explants to treatment groups independent of location and by evaluating stress to failure. CONCLUSIONS: Insulin weakens the structural integrity of equine lamellar explants and an ex vivo model for evaluation of hyperinsulinaemia-induced lamellar failure was established. The summary is available in Spanish - see Supporting Information.


Assuntos
Doenças do Pé/veterinária , Casco e Garras/efeitos dos fármacos , Doenças dos Cavalos/tratamento farmacológico , Hipoglicemiantes/farmacologia , Insulina/farmacologia , Animais , Fenômenos Biomecânicos , Meios de Cultura , Feminino , Doenças do Pé/tratamento farmacológico , Doenças do Pé/etiologia , Doenças do Pé/fisiopatologia , Membro Anterior , Casco e Garras/fisiologia , Doenças dos Cavalos/etiologia , Doenças dos Cavalos/fisiopatologia , Cavalos , Hiperinsulinismo/complicações , Hiperinsulinismo/fisiopatologia , Hiperinsulinismo/veterinária , Modelos Lineares , Masculino , Distribuição Aleatória , Estresse Fisiológico , Falanges dos Dedos do Pé/efeitos dos fármacos , Falanges dos Dedos do Pé/fisiologia
3.
Proc Math Phys Eng Sci ; 473(2200): 20160927, 2017 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-28484335

RESUMO

This paper is a discussion of the hypothesis of weak coupling in statistical energy analysis (SEA). The examples of coupled oscillators and statistical ensembles of coupled plates excited by broadband random forces are discussed. In each case, a reference calculation is compared with the SEA calculation. First, it is shown that the main SEA relation, the coupling power proportionality, is always valid for two oscillators irrespective of the coupling strength. But the case of three subsystems, consisting of oscillators or ensembles of plates, indicates that the coupling power proportionality fails when the coupling is strong. Strong coupling leads to non-zero indirect coupling loss factors and, sometimes, even to a reversal of the energy flow direction from low to high vibrational temperature.

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