Imaging findings in pseudocystic osteosarcoma.

OBJECTIVE: Our purpose was to describe four female patients with osteosarcoma whose clinical and imaging findings primarily suggested either simple or aneurysmal bone cyst. All lesions were osteolytic, intracompartmental, and expanded bone without periosteal reaction. None of the patients presented during the peak age incidence for osteosarcoma. From imaging to histologic diagnosis, the discovery of osteosarcoma ranged from 1 week to 3 years. CONCLUSION: Atypical osteosarcoma may rarely mimic simple or aneurysmal bone cyst radiologically and may show a nonmalignant rate of growth. It may be more frequently encountered in females and may not present during the peak age incidence for osteosarcoma. Microscopically, the tumors were not cystic, necrotic, or telangiectatic but were conventional osteosarcoma and osteoclast-rich osteosarcoma.

Proximity of the posterior cruciate ligament insertion to the popliteal artery as a function of the knee flexion angle: implications for posterior cruciate ligament reconstruction.

PURPOSE: The purpose of this study was to determine if an optimal knee flexion angle existed that would minimize the risk of neurovascular injury from the passage of transtibial hardware during posterior cruciate ligament (PCL) reconstruction. TYPE OF STUDY: Cadaveric. MATERIALS AND METHODS: Fourteen fresh-frozen cadaveric knees were mounted in a Plexiglas apparatus that could be set at 5 different knee flexion angles (0 degrees, 45 degrees, 60 degrees, 90 degrees, and 100 degrees ) while joint distention was maintained. Each knee underwent magnetic resonance imaging in the axial and sagittal planes at each of the 5 flexion angles to determine the distance between the PCL tibial insertion and popliteal artery. RESULTS: The mean distance, over all 5 flexion angles, between the PCL insertion and the popliteal artery in the axial plane was 7.6 mm, whereas the mean distance in the sagittal plane was 7.2 mm. There was a significant increase in distance with progressive flexion in both planes. Maximum mean distances were noted at 100 degrees of flexion in both the axial (9.9 mm) and sagittal (9.3 mm) planes. An artificial line mimicking the path of a transtibial drill passed through the popliteal artery in 10 of 10 cases at the 0 degrees, 45 degrees, 60 degrees, and 90 degrees angles, and in 6 of 10 cases at the 100 degrees angle. CONCLUSIONS: The results of this study suggest that increasing knee flexion reduces, but does not completely eliminate, the risk of arterial injury during arthroscopic PCL reconstruction.

Solitary skeletal hemangioma of the extremities.

OBJECTIVE: To report the clinicopathologic features of solitary skeletal hemangioma of the extremities and to review previous cases in the English language medical literature. PATIENTS: In addition to five of our own cases, 34 literature cases with substantial and 75 with partial clinicopathologic information were found. RESULTS: Our patients, three men and two women, ranged in age from 37 to 83 years (mean 65.6 years). The lesion was an incidental radiologic finding in two patients, while three were symptomatic. In no case was a correct preoperative radiologic diagnosis made, a malignant process being considered as a possibility in all. The hemangiomas were medullary; two involved a metacarpal, two the fibula, and one the humerus. In contrast, previously reported patients were younger (mean age 32 years), predominantly female (60%), and symptomatic in over 90% of cases. The lesion is rare in those younger than age 10 years or older than age 60 years. As in our patients, the long bones are most frequently involved (75%), with the diaphysis or metadiaphysis, as in four of our patients, the most common locations. Although 20% of cases occur in the hands or feet, metacarpal involvement is rare. Medullary origin, as in all of our cases, is most frequent, but 45% of cases are either periosteal (33%) or intracortical (12%). In the literature, cavernous hemangioma is the most frequent type. Three of our hemangiomas were cavernous, one capillary, and one venous, the latter being rarely reported in extremity bones. CONCLUSIONS: Due to the diversity of radiologic patterns produced by skeletal hemangioma, a correct preoperative diagnosis is rarely made. Almost all patients do well, even those with less than complete removal of the lesion; local recurrence is rare. All of our patients were well following either therapeutic or simple diagnostic procedures. Due to the destructive nature of some biopsy procedures, the histologic diagnosis of hemangioma may at times also be problematic.

Imaging the postoperative meniscus.

Patients who have undergone meniscal repair or resection and who develop new symptoms frequently are referred for MR imaging. In the postoperative meniscus, however, the standard MR imaging criteria for meniscal tears cannot be applied to diagnose recurrent or residual tears because signal and shape abnormalities are expected postoperative findings. This article reviews the MR imaging findings that can be used for diagnosing recurrent tears and demonstrates the usefulness of MR arthrography in the evaluation of the postoperative meniscus.

Synovial chondromatosis in a facet joint of a cervical vertebra.

STUDY DESIGN: A case report of a cervical facet joint synovial chondromatosis. OBJECTIVES: To correlate the radiologic and histologic features of vertebral synovial chondromatosis with review of the literature. SUMMARY OF BACKGROUND DATA: Only two previous cases of vertebral facet joint synovial chondromatosis were found in a review of the English language medical literature. METHODS: A 39-year-old woman had severe cervical pain associated with neurologic signs and symptoms in the left upper extremity. Computed tomographic and magnetic resonance imaging studies were performed. RESULTS: Imaging studies showed lytic defects in the laminae of C3 and C4, with intermediate T1 and high T2 signal intensities. The diagnostic impression was that of a lymphangioma or synovial cyst. A laminectomy showed synovial tissue in both the C3-C4 facet joint and the lamina bone. Histologic examination disclosed synovial chondromatosis. CONCLUSIONS: Synovial chondromatosis of the vertebral spine is quite rare, this being only the third reported example. Direct invasion of the cancellous bone, as in this case, also is a very uncommon feature of chondromatosis. It is emphasized that when radiologic studies demonstrate a lesion with cartilaginous characteristics within or juxtaposed to a joint, synovial chondromatosis, despite its rarity, should be included in the differential diagnosis, regardless of the anatomic site.

Pictorial review: magnetic resonance imaging of benign soft tissue masses of the hand and wrist.

Magnetic resonance imaging (MRI) is the imaging method of choice for evaluating the presence and extent of soft tissue masses. It is particularly useful for assessing masses in the wrist and hand, where benign lesions predominate. A specific diagnosis may be made, or strongly suspected, from the characteristic MRI features found in certain conditions like ganglion, haemangioma, arteriovenous malformation, giant cell tumour of the tendon sheath and lipoma.

MR diagnosis of rotator cuff tears of the shoulder: value of using T2-weighted fat-saturated images.

OBJECTIVE: The purpose of this study was to compare the use of fat-saturated T2-weighted spin-echo MR imaging with that of conventional T2-weighted spin-echo MR imaging to detect full- and partial-thickness tears of the rotator cuff of the shoulder, using arthroscopy as the standard for the diagnosis. SUBJECTS AND METHODS: Forty-nine consecutive patients with shoulder pain who had both MR imaging and arthroscopy of their affected shoulders were studied. The study group consisted of 10 patients with full-thickness tears of the rotator cuff, 20 with partial-thickness tears of the rotator cuff, and 19 with intact rotator cuff tendons proved arthroscopically. All patients had T1-weighted, conventional T2-weighted, and fat-saturated T2-weighted MR images obtained in a plane slightly oblique to the coronal plane along the long axis of the supraspinous tendon. The images were divided into two sets, one including both T1-weighted and conventional T2-weighted images, the other including T1-weighted and fat-saturated T2-weighted images. Two musculoskeletal radiologists reviewed each set of MR images in a blinded fashion. The reviewers were asked to decide whether the rotator cuff showed a full-thickness tear, a partial-thickness tear, or no tear on each set of images. In the case of partial-thickness tears, the reviewers were asked to indicate which surface (bursal or joint) of the rotator cuff was affected. These data were correlated with the arthroscopic findings and with each other using McNemar and kappa analysis. RESULTS: Detection of full-thickness tears was excellent for both reviewers using either imaging technique. However, when the fat-saturated technique was used, the sensitivity increased significantly, from 80% to 100%. Detection of partial-thickness tears was poor with conventional spin-echo MR imaging (15%). Although significantly improved when fat saturation was used (35%), detection rates were still lower than rates reported in the literature. Identification of the torn surface of the rotator cuff was correct in 50% of cases in which partial-thickness tears were successfully identified. Fat saturation decreased the specificity of identification of both partial and full-thickness tears of the rotator cuff but significantly increased the specificity with which intact rotator cuffs were identified. CONCLUSION: Use of the fat-saturation technique improved detection of both full-thickness and partial-thickness tears of the rotator cuff on MR images compared with standard spin-echo imaging techniques. Despite this improvement, detection of partial-thickness tears was poor with both techniques. Furthermore, correct identification of which surface of the rotator cuff was torn in patients with partial tears was nearly random.

Acromial arch shape: assessment with MR imaging.

PURPOSE: To test the hypothesis that acromial shape is comparable on supraspinatus outlet view radiographs and parasagittal magnetic resonance (MR) images. MATERIALS AND METHODS: Supraspinatus outlet view radiographs of a dried scapula were obtained in the neutral position and with various degrees of caudal, cranial, anterior, and posterior angulation. Sagittal MR images of 41 asymptomatic and 39 symptomatic shoulders were reviewed and compared with outlet view radiographs from the 39 symptomatic cases. Acromial shape was assessed with published classification schemes. RESULTS: Minor variations in angulation produced changes in apparent acromial shape and thickness on the radiographs. MR imaging from a lateral to a more medial section changed the shape or thickness grade in 39 of 41 asymptomatic shoulders. There was poor correlation between findings at radiographic and MR assessment of acromial shape in the symptomatic group. CONCLUSION: Apparent acromial shape is sensitive to minor changes in radiographic technique and MR section viewed.

MR appearance of cystic fibrous dysplasia.

The radiologic and MR appearances of cystic fibrous dysplasia (FD) along with pathologic correlation are reported in a symptomatic patient. As a guide for operative intervention, MRI is helpful in both characterizing the lesion and its internal structure and determining the extent of osseous involvement. Cystic FD without an aneurysmal bone cyst component has not been previously reported in the radiologic literature.

The normal shoulder: common variations that simulate pathologic conditions at MR imaging.

The appearance of the supraspinatus tendon and anterior capsular mechanism was analyzed in 60 asymptomatic shoulders with magnetic resonance (MR) imaging. The images were reviewed with special attention to findings that simulate pathologic conditions, as defined by means of currently accepted criteria. On T1-weighted and proton-density (PD) spin-echo (SE) images, intermediate signal intensity was present within the supraspinatus tendon in most shoulders. Focal signal intensity within the distal tendon was particularly common finding, being present in 95% (57 of 60) of shoulders on PD images. Focal obliteration of the subacromial-subdeltoid fat stripe and acromioclavicular joint arthrosis were seen in 95% (57 of 60) and 48% (29 of 60) of the subjects, respectively. There was considerable variation in the shape of the anterior glenoid labrum-glenohumeral ligament (GHL) complex. The labrum may appear triangular, round, crescentic, or absent. The middle and inferior GHLs lie in proximity to the upper half of the anterior labrum; the cleavage plane between the ligaments and the labrum can mimic a tear at MR imaging.

Characterization of musculoskeletal masses using dynamic Gd-DTPA enhanced spin-echo MRI.

Early studies evaluating the utility of Gd-diethylenetriamine pentaacetic acid (DTPA) enhanced MR imaging for characterization of musculoskeletal masses have demonstrated inconsistent and often conflicting results. In this study a new method, dynamic Gd-DTPA enhanced rapid acquisition spin echo MR imaging, was implemented in the evaluation of 18 musculoskeletal lesions and the enhancement features of these lesions were analyzed. Lesions were evaluated before, during, and sequentially following bolus Gd-DTPA injection. Analysis of intensity, volume, timing of onset, progression, uniformity, and pattern of enhancement did not demonstrate significant differences between benign (n = 8) and malignant (n = 10) masses. Significant variations in enhancement were noted in different regions within these masses, which limits the utility of previous dynamic contrast enhanced methods that provide only a single imaging slice for analysis, and are therefore subject to sampling error. This pilot study indicates no advantage for using dynamic Gd-DTPA enhanced imaging for qualitative lesion characterization.

Magnetic resonance imaging of ankle injuries.

Stress placed on the ankle from sport activity predisposes it to a variety of injuries. MRI, with its multiplanar capability and excellent soft tissue contrast, is uniquely suited for examining the complex anatomy of the ankle. It is the procedure of choice for imaging suspected tendon and cartilage damage. It is also highly sensitive in detecting radiographically occult bone injuries. This review first addresses technical factors important in generating high-resolution images that are crucial for accurate diagnosis in this area. Pathogenesis and MRI appearance of commonly encountered sport-related soft tissue and bone injuries around the ankle are presented and discussed.

Calcaneal and pelvic fractures: diagnostic evaluation by three-dimensional computed tomography scans.

A major application of three-dimensional (3D) computed tomography (CT) is in the imaging of the skeleton. 3D CT has a potentially important role in determining the presence, type, and extent of fractures, especially of the calcaneus and pelvis. The objective of this study was to compare the diagnostic sensitivity and specificity of 3D CT, CT slices, and plain radiography in the detection and characterization of calcaneal and pelvic fractures. 3D CT reconstructions were obtained by two methods, surface reconstruction and volumetric techniques. Twenty-eight patients were imaged with CT, 3D CT, and plain radiography. The opinion of a musculoskeletal radiologist with access to all images plus clinical history, surgical findings, and follow-up findings was taken as truth. Four additional musculoskeletal radiologists read these cases in a blinded fashion and ranked the modalities with regard to perceived utility. Receiver operating characteristic analysis was used to determine the relative value of each modality in terms of diagnostic quality. All imaging modalities performed comparably in the diagnosis of fractures. CT slices and plain-films were the most useful for more difficult diagnostic tasks such as fracture stability, and the presence of comminution and estimation of the number of fragments. The results suggest that for skeletal areas with complicated anatomy (such as the pelvis and calcaneus), the diagnostic value of 3D CT is often equivalent to that of conventional methods.

MR examination of the knee: interpretation with multiscreen digital workstation vs hardcopy format.

A multiscreen imaging workstation was compared with conventional hardcopy format for diagnostic interpretation of MR images of the knee. MR examinations from 30 patients were interpreted by two observers using film displayed both on a standard film panel alternator and an eight-screen digital workstation. Arthroscopic examination of these patients disclosed 30 meniscal tears and five anterior cruciate ligament tears in 28 patients. Two patients had normal arthroscopic examinations. The MR examinations were evaluated with a five-point confidence rating scale. Results were correlated with arthroscopic findings, and receiver-operating-characteristic curves were generated from these data. No significant difference was found between the areas under the receiver-operating-characteristic curves for film and digital display. The time required for image interpretation was greater when using the digital workstation than when using the film by a factor of approximately 2.7. Our data indicate that a multiscreen digital workstation can be used for interpreting MR examinations of the knee without impairment of diagnostic performance, but with increased time required for image interpretation when compared with radiographic film and a film panel alternator.

Renal transplants: can acute rejection and acute tubular necrosis be differentiated with MR imaging?

Magnetic resonance (MR) imaging was used in 40 renal transplant recipients to determine whether this modality can enable distinction of acute tubular necrosis (ATN) and acute rejection by means of corticomedullary differentiation (CMD). Each patient underwent initial MR imaging after allograft renal transplantation. Twenty-nine of these 40 patients (72%) also underwent subsequent follow-up MR imaging. Seventeen studies were obtained during episodes of ATN; 12 of these studies (71%) showed poor CMD. Eleven studies were obtained during episodes of acute rejection; eight of these studies (73%) showed poor CMD. In addition, six of seven studies (86%) showing various combinations of renal disease (ATN, acute rejection, chronic rejection, and cyclosporine toxicity) also showed poor CMD. Loss of CMD is reversible after improvement of ATN and acute rejection. Because loss of CMD is a nonspecific though sensitive sign reflecting renal transplant dysfunction, MR imaging is of limited value in the differentiation of ATN from acute rejection.

Cross-sectional imaging of the patellofemoral joint and surrounding structures.

Computed tomography (CT) and magnetic resonance (MR) imaging are extremely useful in the accurate diagnosis of anterior knee pain, a common complaint arising from numerous causes (including fracture, chondromalacia patellae, and alignment and tracking abnormalities). Plain CT is effective for evaluating intraosseous lesions of the knee. Although CT arthrography provides excellent visualization of the patellar articular cartilage, the technique is expensive and invasive. Cine CT is an excellent method for assessing patellofemoral tracking and alignment. Kinematic MR imaging can also perform this function. In addition, MR imaging can provide valuable information concerning the status of patellar cartilage. Although MR imaging can accurately show high-grade chondromalacia patellae, it is less accurate in the detection of low-grade disease. The authors believe that MR imaging and plain radiography offer radiologists the greatest latitude in making a specific diagnosis of the cause of anterior knee pain; however, CT is a useful alternative.

Magnetic resonance imaging of peripheral nerve sheath tumors. Assessment by numerical visual fuzzy cluster analysis.

A retrospective, nonblinded review of ten nerve sheath tumors (four malignant) selected for pathologic proof and complete magnetic resonance (MR) evaluation was performed to assess the primary tumor location, signal pattern, and extent of reactive zone. A modification of visual fuzzy cluster analysis (VFCA) that emphasized the number of visual fuzzy clusters in each mass was developed to assess the neural tumors. The MR findings were correlated with the findings at surgery and histopathology. There were six men and four women, aged 19 to 62 years (mean, 43). Nine tumors involved the lower extremity. In all tumors, MRI correctly identified the nerve trunk of origin. Tumor dimensions were generally overestimated by MRI. Three internal signal patterns were observed: homogeneous (1/1 benign), finitely inhomogeneous (5/5 benign), and hectically inhomogeneous (4/4 malignant). The number of visual fuzzy clusters (VFCRs) for each sequence did not allow reliable separation of benign and malignant entities, but when considered in aggregate, benign and malignant lesions segregated in different clusters. This implies that the likelihood of malignancy increases as the number of MR-identifiable tissue types per lesion increase. Three types of reaction (edema) were observed best on long repetition time/echo time (TR/TE) sequences, confined to immediate peritumoral region, intracompartmental, and extracompartmental. The first two patterns correlated well with clinicopathologic findings; however, the third pattern did not. Separation of indolent (benign) cellular masses from aggressive (malignant) ones by MR characteristics is difficult but VFCA shows promise for aiding this differentiation and deserves further investigation in larger study populations.

The knee after partial meniscectomy: MR imaging features.

The magnetic resonance (MR) examinations of 51 menisci treated by means of partial meniscectomy were reviewed. Menisci were divided into three groups: group 1, near normal length without osteoarthritis; 2, substantially shortened without osteoarthritis; and 3, any length with osteoarthritis. Group 1 menisci resembled normal menisci except for mild shortening and frequent signal inhomogeneity (56%). Group 2 menisci varied in appearance, with marked contour irregularity simulating fragmentation in 40% of segments despite a normal postoperative appearance at follow-up arthroscopy. Group 3 menisci appeared similar to menisci of the same length without osteoarthritis. Arthroscopic correlation, available for 23 menisci (45%), confirmed the MR diagnosis of a tear in 11 and no tear in 49 and revealed an unsuspected tear in three meniscal segments. There is a spectrum of normal MR appearances after partial meniscectomy. Standard MR criteria can be used to diagnose tears in the absence of marked contour irregularity; however, the diagnosis of tears of segments with marked contour irregularity must be made cautiously, since this irregularity can mimic a tear and was not predictive of an arthroscopically visible tear.

Subtalar arthrosis: evaluation with CT.

The surgical implantation of a Silastic wedge into the lateral subtalar joint (subtalar arthrosis) is designed to restrict the osseous malalignment associated with a flexible or neurogenic flatfoot deformity. We used CT to examine patients who had persistent pain after a subtalar arthrosis and retrospectively reviewed our experience with CT scans of 13 subtalar implants (seven patients) during a 3.5-year period. The CT scans of four asymptomatic subtalar implants showed each implant in the expected position and orientation, and the findings were considered normal. Conversely, the findings on CT scans of all nine painful implants (seven patients) were interpreted as abnormal. The scans showed oblique orientation of four implants (44%), loosening of three implants (33%), extruded methyl methacrylate in the subtalar joint in two implants (22%), and abnormal calcaneal recession in two implants (22%). Five of the nine painful implants were revised with improvement or resolution of symptoms. Our experience suggests that CT scanning of the subtalar joint can show the position and orientation of a subtalar implant and identify causes of persistent pain after a subtalar arthrosis.