1.
J Physiol
; 239(3): 435-42, 1974 Jun.
Artigo
em Inglês
| MEDLINE
| ID: mdl-4854790
RESUMO
The timed uptake of (131)I-labelled human serum albumin was used as an index of regional perfusion in the isolated rat kidney.1. Arginine vasopressin in doses of 1, 5 and 10 muu./ml. of perfusate decreased papillary perfusion. Total renal perfusion was decreased only by the 5 muu. dose.2. Ornithine-8-vasopressin in doses of 5 and 10 muu./ml. of perfusate decreased papillary perfusion. Total renal perfusion was decreased only by the 10 muu. dose.3. When the relative viscosity of the perfusate was increased to a value of 2.0 from the control value of 1.7, both papillary perfusion and total renal perfusion were reduced.4. Arginine vasopressin further reduced papillary flow in kidneys perfused with high viscosity artificial plasma.
Assuntos
Rim/irrigação sanguínea , Vasopressinas/farmacologia , Animais , Arginina/administração & dosagem , Técnicas In Vitro , Rim/efeitos dos fármacos , Medula Renal/irrigação sanguínea , Medula Renal/efeitos dos fármacos , Masculino , Ornitina/administração & dosagem , Perfusão , Ratos , Fluxo Sanguíneo Regional/efeitos dos fármacos , Soroalbumina Radioiodada , Vasopressinas/administração & dosagem , Viscosidade
2.
Clin Sci Mol Med
; 46(5): 647-50, 1974 May.
Artigo
em Inglês
| MEDLINE
| ID: mdl-4366782