RESUMO
The trials were performed on 43 patients at the age from 18 to 73 years, operated in connection to brain tumors. The clophelinum--fentanil anesthesia was revealed as preventing cerebral metabolism and blood circulatory disorders, brain edema development both at the operation and at the early postoperative periods.
Assuntos
Analgésicos Opioides/administração & dosagem , Anestesia Intravenosa , Neoplasias Encefálicas/cirurgia , Encéfalo/irrigação sanguínea , Encéfalo/metabolismo , Clonidina/administração & dosagem , Fentanila/administração & dosagem , Hemodinâmica/fisiologia , Oxigênio/sangue , Oxigênio/farmacocinética , Simpatolíticos/administração & dosagem , Adolescente , Adulto , Idoso , Humanos , Pessoa de Meia-Idade , Modelos BiológicosRESUMO
Combined spinal anesthesia with the use of hyperbaric solution of lignocaine at an average dose of (69.4 +/- 1.4) mg and morphine hydrochloride at a dose of 0.3 mg was used in 50 patients with II-IV degree anesthesiologic risk during one-stage appendectomy. Effective intraoperative anesthesia was achieved in (96.2 +/- 2.5) % of cases. Duration of postoperative analgesia was (26.8 +/- 1.1) h. Suppression of breathing, hyperalgesia on termination of the effect of a local anesthetic were not noted. In (50.1 +/- 1.7) % of the patients, intraoperative hypotension was revealed. After the operation, nausea was noted in (20 +/- 11.5) % of these patients, vomiting--in (6.0 +/- 2.3) %, itch at the site of puncture--in (22.0 +/- 10.4) %, shiver--in (2.0 +/- 1.4) %.