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Phys Med Biol ; 65(9): 095009, 2020 05 11.
Artigo em Inglês | MEDLINE | ID: mdl-32101806

RESUMO

This work proposes using artificial neural networks (ANNs) for the regression of the dosimetric quantities employed in mammography. The data were generated by Monte Carlo (MC) simulations using a modified and validated version of the PENELOPE (v. 2014) + penEasy (v. 2015) code. A breast model of a homogeneous mixture of adipose and glandular tissue was adopted. The ANNs were constructed using the Keras and scikit-learn libraries for mean glandular dose (MGD) and air kerma (Kair ) regressions, respectively. In total, seven parameters were considered, including the incident photon energies (from 8.25 to 48.75 keV), breast geometry, breast glandularity and Kair acquisition geometry. Two ensembles of five ANNs each were formed to calculate MGD and Kair . The normalized glandular dose coefficients (DgN) were calculated using the ratio of the ensemble outputs for MGD and Kair . Polyenergetic DgN values were calculated by weighting monoenergetic values by the spectrum bin probabilities. The results indicate a very good ANN prediction performance when compared to the validation data, with median errors on the order of the average simulation uncertainties (≈ 0.2%). Moreover, the predicted DgN values are in good agreement compared with previously published works, with mean (maximum) differences up to 2.2% (9.4%). Therefore, it is shown that ANNs could be a complementary or alternative technique to tables, parametric equations and polynomial fits to estimate DgN values obtained via MC simulations.


Assuntos
Mamografia/métodos , Redes Neurais de Computação , Tecido Adiposo/crescimento & desenvolvimento , Tecido Adiposo/efeitos da radiação , Feminino , Humanos , Glândulas Mamárias Humanas/diagnóstico por imagem , Glândulas Mamárias Humanas/efeitos da radiação , Mamografia/normas , Método de Monte Carlo , Doses de Radiação
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