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Ocul Immunol Inflamm ; 25(1): 97-104, 2017 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-26807675

RESUMO

OBJECTIVE: To describe the clinical spectrum and outcome of patients with presumed tubercular uveitis and choroidal involvement. METHODS: A retrospective case series nested in a cohort study was enrolled at a tertiary referral eye care center in the UK. Failure was defined as recurrence of lesion within 6 months of completion of antitubercular therapy (ATT) or corticosteroid therapy. RESULTS: Seventy-seven patients with presumed ocular tuberculosis and choroidal involvement were included in the study. Mean age was 45.5 ± 15.7 years, 44 (57.1%) patients were male, and 51 (66.2%) presented with bilateral disease. Choroidal granuloma was the most frequent clinical presentation (n = 27, 35.07%), followed by multifocal choroiditis (n = 24, 31.17%) and serpiginous-like choroiditis (n = 18, 23.38%). Quantiferon Gold in Tube Test (QFT) was positive in 64 (83.11%) patients. Fifty (64.94%) patients received ATT. CONCLUSIONS: Choroidal involvement in presumed ocular tuberculosis can present with a variable spectrum. Treatment failure rates were equivalent between ATT and non-ATT treated groups.


Assuntos
Corioidite/epidemiologia , Doenças Endêmicas/estatística & dados numéricos , Granuloma/epidemiologia , Tuberculose Ocular/epidemiologia , Adulto , Idoso , Idoso de 80 Anos ou mais , Antituberculosos/uso terapêutico , Corioidite/diagnóstico , Corioidite/tratamento farmacológico , Quimioterapia Combinada , Feminino , Glucocorticoides/uso terapêutico , Granuloma/diagnóstico , Granuloma/tratamento farmacológico , Humanos , Testes de Liberação de Interferon-gama , Londres/epidemiologia , Masculino , Pessoa de Meia-Idade , Coroidite Multifocal , Estudos Retrospectivos , Teste Tuberculínico , Tuberculose Ocular/diagnóstico , Tuberculose Ocular/tratamento farmacológico , Adulto Jovem
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