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1.
Int J Infect Dis ; 116: 271-272, 2022 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-34995777

RESUMO

The Delta variant of concern (VOC) of SARS-CoV-2 has become dominant worldwide. In this article, we report a cluster caused by B.1.617.2 harboring the additional mutation of concern (MOC) F490S. We observed that 5 fully vaccinated subjects aged between 47 and 84 years were infected with this variant. The immune escape mutation F490S, first identified in the Lambda VOI, appears to impair vaccine efficacy and is rapidly increasing in prevalence worldwide.


Assuntos
COVID-19 , SARS-CoV-2 , Idoso , Idoso de 80 Anos ou mais , COVID-19/epidemiologia , Vacinas contra COVID-19 , Humanos , Pessoa de Meia-Idade , Mutação , SARS-CoV-2/genética
2.
Emerg Infect Dis ; 27(12): 3180-3182, 2021 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-34499599

RESUMO

The Delta variant of concern of severe acute respiratory syndrome coronavirus 2 is dominant worldwide. We report a case cluster caused by Delta sublineage B.1.617.2 harboring the mutation E484K in Italy during July 11-July 29, 2021. This mutation appears to affect immune response and vaccine efficacy; monitoring its appearance is urgent.


Assuntos
COVID-19 , SARS-CoV-2 , Humanos , Itália/epidemiologia , Mutação
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