RESUMO
A pilot study on the prevalence of neurological disorders in Sicily was carried out with a protocol never previously used in Italy. A screening questionnaire was administered to 1,601 subjects of a community, designed to identify patients with cerebrovascular diseases, epilepsy, extrapyramidal syndromes, peripheral neuropathies, migraine and intracranial neoplasms. Of 262 subjects who were identified as likely to be suffering from neurological illness, 248 (94.6%) were examined by a neurologist. Of these, 8.9% were found to be normal, 46.8% were suffering from non-neurological diseases, 44.3% had one or more neurological diseases (prevalence of 6.8%). This pilot study proved to be a good starting-point for a future major survey.
Assuntos
Doenças do Sistema Nervoso Central/epidemiologia , Adolescente , Adulto , Idoso , Criança , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Projetos Piloto , Sicília , Inquéritos e QuestionáriosAssuntos
Epilepsias Parciais/induzido quimicamente , Doenças Neuromusculares/induzido quimicamente , Fenitoína/efeitos adversos , Psicoses Induzidas por Substâncias/etiologia , Adulto , Relação Dose-Resposta a Droga , Eletroencefalografia , Epilepsias Parciais/tratamento farmacológico , Potenciais Evocados/efeitos dos fármacos , Feminino , Humanos , Fenitoína/uso terapêuticoRESUMO
Diazepam i.v. injected at the dose of 5 mg/Kg on a group of 14 Rhode-Island-Red chicks was able to antagonize and prevent the interictal EEG pattern induced by cefazolin i.v. Since cefazolin epilepsy is most probably dependent on a receptorial antagonism with GABA, these data seem to confirm the GABA-ergic nature of cefazolin epilepsy.
