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1.
Z Gerontol Geriatr ; 51(4): 411-417, 2018 Jun.
Artigo em Alemão | MEDLINE | ID: mdl-28144788

RESUMO

BACKGROUND: Expertise in geriatrics in the field of ambulatory and hospital-based treatment does not have access to comparable medical specialist structures, such as those in internal medicine and neurology; therefore, it is recommended that geriatric diagnostics by general practitioners can be supported by networking with hospital-based geriatric centers for geriatric counseling. The attitudes and experiences of both faculties in Germany are, however, not well known. METHODS: Representative samples of general practitioners and hospital-based faculty departments for internal medicine in two regions of Germany (Baden-Württemberg and Hessen) were identified using a systematic selection method. All departments of geriatrics in these regions were also contacted. Participants were asked to give their attitudes and experiences regarding geriatric counseling using a questionnaire. RESULTS: Responses to the questionnaire were received from 48 general practices (14.9%), 42 internal medicine departments (38.5%) and 25 hospital-based geriatric centers (34.7%). Of the general practices 79.2% reported performing geriatric assessments but only 31.3% had access to geriatric counseling. Of the faculties of internal medicine 71.4% reported providing geriatric counseling of which 16.7% also provided counseling on an outpatient basis. With respect to the spectrum of actual reasons for geriatric counseling, initiation of rehabilitative measures was the main reason in both geriatric and internal medicine departments. There were differences in the estimation of suitable rating topics for geriatric counseling. Geriatric departments more frequently indicated preventive aspects compared to general internal medicine (80% vs 47.6%) and general practices (56.3%). With respect to the domain level, general practitioners rated these in the order of cognition (72.9%), social situation (70.8%), emotion (50%), locomotion (50%) and incontinence (27.1%). Noteworthy was that they also rated much lower compared to hospital-based providers particularly with respect to locomotion and incontinence problems. CONCLUSION: Geriatric assessment is widely used by general practitioners and there is generally a positive attitude to geriatric counseling and networking with hospital-based geriatric centers. At present, only a minority of general practitioners find local providers of geriatric counseling. Preventive aspects do not reach the same significance as rehabilitation topics and this discloses some potential for improvement. Differences in rating usefulness between the two groups may be explained by competing providers, e. g. specialists in these fields.


Assuntos
Aconselhamento , Clínicos Gerais , Avaliação Geriátrica , Idoso , Atitude , Geriatria , Alemanha , Humanos , Motivação , Inquéritos e Questionários
2.
Am J Physiol Heart Circ Physiol ; 279(1): H102-9, 2000 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-10899046

RESUMO

Fasting [(18)F]fluoro-2-deoxyglucose (FDG) uptake is increased in viable, chronically dysfunctional myocardium, but the relationship to acute episodes of ischemia remains undefined. To investigate FDG uptake in acute stunning, chronically instrumented pigs (n = 9) and sham controls (n = 8) were studied while in a fasted, closed-chest, anesthetized state. One-hour partial occlusion reduced subendocardial flow from 1.24 +/- 0.14 to 0.35 +/- 0.06 ml. min(-1). g(-1) and wall thickening from 16.8 +/- 2.1 to 3.7 +/- 0.7%. Regional function remained depressed during reperfusion (8.3 +/- 1. 4%) despite the return of flow to resting levels. Triphenyl tetrazolium chloride staining showed no irreversible injury. FDG uptake in stunned myocardium was variably increased and averaged 1. 5-fold higher than that of normal regions, with no consistent transmural variation. Subgroup analysis showed that variability in FDG uptake was related to alterations in insulin levels that varied directly with ischemic risk region.


Assuntos
Fluordesoxiglucose F18/farmacocinética , Isquemia Miocárdica/metabolismo , Miocárdio Atordoado/metabolismo , Miocárdio/metabolismo , Animais , Pressão Sanguínea , Circulação Coronária , Coração/fisiologia , Coração/fisiopatologia , Frequência Cardíaca , Hemodinâmica , Reperfusão Miocárdica , Miocárdio Atordoado/fisiopatologia , Compostos Radiofarmacêuticos/farmacocinética , Valores de Referência , Suínos , Distribuição Tecidual
5.
J Forensic Sci ; 28(2): 489-95, 1983 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-6683302

RESUMO

A 24-year-old black female presented a live birth of six-months gestation. The 700-g neonate survived for 11 h. After toxicology revealed the presence of pentazocine and tripelennamine (T's and Blues), the mother admitted to using this combination intravenously 9 h previous to admission. Concentrations of pentazocine and tripelennamine were simultaneously determined by gas-liquid chromatography (GLC) combined with nitrogen selective detection. Analyses were performed on a 3% OV-101 column, with the added internal standard, dexbrompheniramine. Both pentazocine and tripelennamine were qualitatively confirmed by their electron impact mass spectra. Concentrations of pentazocine and tripelennamine in various fluids and tissues were determined.


Assuntos
Doenças do Prematuro/induzido quimicamente , Troca Materno-Fetal/efeitos dos fármacos , Trabalho de Parto Prematuro/induzido quimicamente , Pentazocina/intoxicação , Transtornos Relacionados ao Uso de Substâncias/complicações , Tripelenamina/intoxicação , Adulto , Cromatografia Gasosa , Feminino , Cromatografia Gasosa-Espectrometria de Massas , Humanos , Recém-Nascido , Espectrometria de Massas , Pentazocina/análise , Gravidez , Efeitos Tardios da Exposição Pré-Natal , Tripelenamina/análise
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