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1.
Eur Ann Otorhinolaryngol Head Neck Dis ; 140(4): 165-170, 2023 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-36609114

RESUMO

PURPOSE: To evaluate long-term oncological outcome for patients with selected glottic squamous cell carcinoma (SCC) classified as T3N0M0 treated by supracricoid partial laryngectomy (SCPL). MATERIALS AND METHODS: Analysis of an inception cohort of 46 patients with isolated untreated SCC classified as T3N0M0 and minimum 10-year follow-up, consecutively treated by SCPL between 1982 and 2012 in a French university teaching hospital. The main endpoint was 5- and 10-year actuarial survival and local control estimates. Accessory endpoints comprised cause of death, screening for variables decreasing survival and increasing risk of local recurrence, oncologic consequences of local recurrence, and laryngeal preservation rate. RESULTS: Five- and 10-year actuarial survival was 78.1%, and 53.3%, respectively. The main causes of death were intercurrent disease and metachronous second primary, each in 33.3% of cases. Postoperative mortality (aspiration pneumonia) was 2.1%. There were no significant correlations between survival and any study variables. Five- and 10-year local control was 90.5%. Overall local recurrence varied significantly (P=0.003), from 2.3% with negative margins (R0) to 100% with positive margins (R1) and/or dysplasia. Local recurrence was associated with a significantly (P<0.005) increased risk of nodal failure and distant metastasis, and reduced survival. Overall laryngeal preservation was 89.1%. CONCLUSION: The present results suggest that SCPL should continue to be taught and that this type of partial laryngeal surgery should be included in the various organ-sparing strategies considered in advanced laryngeal cancer.


Assuntos
Carcinoma de Células Escamosas , Neoplasias de Cabeça e Pescoço , Neoplasias Laríngeas , Humanos , Carcinoma de Células Escamosas/patologia , Laringectomia/métodos , Resultado do Tratamento , Carcinoma de Células Escamosas de Cabeça e Pescoço/cirurgia , Neoplasias Laríngeas/patologia , Estudos Retrospectivos , Neoplasias de Cabeça e Pescoço/cirurgia , Recidiva Local de Neoplasia/cirurgia , Taxa de Sobrevida
2.
Eur Ann Otorhinolaryngol Head Neck Dis ; 140(3): 131-134, 2023 May.
Artigo em Inglês | MEDLINE | ID: mdl-35902353

RESUMO

OBJECTIVE: To describe the key technical points for preserving the great auricular nerve during parotidectomy for tumor, and to discuss the literature regarding the benefits, limitations and indications for nerve-sparing surgery. Data suggested that great auricular nerve preservation should be discussed in the preoperative consultation, attempted intraoperatively and mentioned in the operative report once parotidectomy completed.


Assuntos
Glândula Parótida , Neoplasias Parotídeas , Humanos , Glândula Parótida/cirurgia , Neoplasias Parotídeas/cirurgia , Qualidade de Vida , Complicações Pós-Operatórias/prevenção & controle
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