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Scand J Infect Dis ; 40(9): 761-5, 2008.
Artigo em Inglês | MEDLINE | ID: mdl-19086249

RESUMO

Aerococcus sanguinicola is a Gram-positive coccus first described in 2001. Infections in humans are rare but the use of 16S rRNA gene sequencing and improved phenotypic methods has facilitated the identification of A. sanguinicola. We report here 6 cases of A. sanguinicola bacteraemia, 2 of which were associated with infective endocarditis. Most patients were elderly (median age 70 y) and had underlying neurological disorders including dementia, cerebral degeneration, and myelomeningocele. The primary focus of infection was the urinary tract in 3 cases and the gallbladder in 1; no focus was detected in 2 cases. Long-term prognosis was poor reflecting the frailty of the patients. All strains were susceptible to penicillin, ampicillin, cefuroxime, vancomycin, erythromycin, and rifampicin. The optimal treatment of infection with A. sanguinicola has yet to be determined.


Assuntos
Bacteriemia , Infecções por Bactérias Gram-Positivas , Streptococcaceae , Adulto , Idoso , Bacteriemia/microbiologia , Bacteriemia/fisiopatologia , Dinamarca/epidemiologia , Endocardite Bacteriana/microbiologia , Feminino , Doenças da Vesícula Biliar/microbiologia , Infecções por Bactérias Gram-Positivas/microbiologia , Infecções por Bactérias Gram-Positivas/fisiopatologia , Humanos , Masculino , Pessoa de Meia-Idade , RNA Ribossômico 16S/genética , Análise de Sequência de DNA , Streptococcaceae/classificação , Streptococcaceae/genética , Streptococcaceae/isolamento & purificação , Streptococcaceae/patogenicidade , Infecções Urinárias/microbiologia
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