Some biochemical parameters of blood plasma of turkey-hens following administration of 1,2,4-triasole derivative.

The present study involved 180 slaughter turkey-hens of heavy Big-6 type divided into four groups (in triplicate repetition for 15 birds). All the birds were fed with the same standard full-dose mixtures in 5-stage system. The turkey-hens of groups I, II and III were given 1,2,4-triasole derivative (3-(2-pyridil)-4-phenyl-1,2,4-triasole-5-carboxylic acid), which has antibacterial, antifungal and immunomodulating properties, in amount of 50, 75 and 100 microg per 1 dm3 of water. Group IV--control was given water without the additive. The 1,2,4-triasole derivative was given to drinking water, starting from the first day of bird's life and for the whole rearing period. The present results of biochemical analysis of blood plasma showed that addition of examined substance significantly reduced concentration of protein, glucose, triglycerides and uric acid as compared to control. It was stated that tested 1,2,4-triasole derivative elevated the level of HDL fraction percentage and alkaline phosphatase activity in blood plasma.

Influence of garlic, synthetic 1,2,4-triasole derivative and herbal preparation echinovit C on selected indices of turkey-hens non-specific immunity.

Successful results of earlier studies on testing the immune-modulating and anti-microbial properties of 1,2,4-triasole derivative as well as benefitial application of natural bio-stimulators in animal's prophylaxis and treatment inspired us to undertake further investigations. The aim of the present study was to evaluate and compare the prophylaxis effects of two natural immune-modulating agents, garlic (Allium sativum) extract and Echinovit C preparation and synthetic derivative of 1,2,4-triasole on non-specific immunity indices in slaughter turkey-hens. The results obtained suggest that the strongest stimulatory effect is exerted by garlic followed by 1,2,4-triasole derivative and Echinacea juice. Immune-modulating action of the substances applied was manifested by an increase in cellular immune parameters: the percentage of phagocyting cells, NBT-positive granulocytes and lysozyme level.

[Alanine and aspartate transaminase and acid and alkaline phosphatase activities in the blood serum in relation to the protein and energy levels in the pigs' feeds]. / Aktywnosc transaminazy alaninowej i asparaginianowej oraz fosfatazy kwasnej i zasadowej w surowicy krwi w zaleznosci od poziomu bialka i energii w zywieniu tuczników.

The activity of alanine and asparagine transaminase and of acid and basic phosphatase was studied in blood serum of 72 porkers of the Polish large-white breed, fed with PT-2 feeds of various protein and energy levels. It was found that the activity of both transaminases in blood serum depended on the protein-energy level of the diet. The activity of transaminases was not found to increase at the protein content compatible with the standard and at increased energy value of the feeds, whereas the same protein level and decreased energy amount caused a decrease in the activity of alanine and asparagine transaminase. At a decreased protein content in the diet the activity of transaminases in plasma was lower than in the porkers on a diet containing protein according to the standard. An increased amount of energy with a decreased protein content in the diet did not affect the activity of asparagine transaminase but slightly stimulated alanine transaminase, whereas a decrease in the amount both of energy and protein in the diet caused an increase in the activity of both transaminases. Acid and basic phosphatase were not adequate indices of changes in the organism of the porkers in relation to the protein-energy level of their diet.