RESUMO
The purpose was to analyze tibial plateau fractures (TPF) by computed tomography (CT) by creating a frequency map (FM). We hypothesized that a FM shows clinically important aspects of involvement that are not expressed in classic classifications. 185 TPF were retrospectively evaluated in this single center study. We created a FM onto an axial template of an intact subarticular tibial plateau and separated the joint surface in 9 areas, counted the frequency of involvement. The FM gives information of location and grade of damage and expressed three major fracture areas in 76%. 5 specific fracture types add up to 51%. The dorsal parts of the tibial plateau are involved in a higher percentage (+8%). True lateral fractures are less often than plane radiographs suggest. An impression was found in 50%. The complexity of TPFs is high, but 5 specific types could be identified in >50%. The complexity is not sufficiently covered in common classifications, especially the dorsal involvement. The FM is a simple and useful tool that complements common classifications and can be used as guideline for surgical treatment.
RESUMO
OBJECTIVE: To compare different magnetic resonance imaging (MRI) based algorithms for assessment of spinal inflammation in patients with ankylosing spondylitis (AS) being treated with disease modifying drugs. METHODS: Eleven patients (10 men, 1 woman) who fulfilled modified New York diagnostic criteria and had severe disease [Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) > 4] were given intravenous infusion of infliximab (Remicade, 5 mg/kg) for 96 weeks. Whole-spine MRI was done at 0, 24, and 54 weeks. Measurements of the Ankylosing Spondylitis Spinal MRI Activity Score (ASspiMRI), paravertebral inflammatory lesion count (pILC), contrast:noise ratio (CNR) measurements of defined inflammatory lesions, and other scores together with C-reactive protein concentration were made at each visit. Examinations were anonymized and randomly presented twice to 2 radiologists. The significance of any changes in scores, their correlation with the BASDAI, and interobserver and intraobserver correlations were calculated. RESULTS: The mean (+/- SD) BASDAI improved from 7.2 (+/- 1.5) to 1.3 (+/- 0.9) after 54 weeks (p < 0.001), and the ASspiMRI score improved from 12.0 (+/- 8.0) to 0.2 (+/- 0.5) (p < 0.001). Correlations between ASspiMRI score and BASDAI were 0.831, 0.746, and 0.369 (p < 0.001 each). The pILC improved significantly (p < 0.01). CNR showed no correlation with any clinical score. CONCLUSION: The ASspiMRI score performed best for assessment and quantification of spinal inflammation and disease activity in patients with AS, but should also quantify paravertebral inflammatory lesions, since we could show that this will significantly improve its correlation to clinical scores and increase its sensitivity to mild inflammatory processes.
