RESUMO
The objective of the paper was to study the developmental continuity of working memory function from infancy to preschool age. At the age of 10 to 11 months 44 participants completed delayed response task (A-not-B) that measures working memory function. Between 5 and 7 years of age the same participants performed three tasks assessing working memory for temporal order in auditory and visual modalities and a control task measuring short-term visuospatial memory. The dependence of temporal-order memory at preschool age on individual level of infant working memory was found for all methods of measurement despite the differences in way of presentation and reproducing of the stimuli order. Results indicate direct continuity in the development of working memory function from infancy to preschool age.
Assuntos
Desenvolvimento Infantil , Memória de Curto Prazo , Pré-Escolar , Feminino , Humanos , Lactente , Masculino , Testes NeuropsicológicosAssuntos
Atenção/fisiologia , Desenvolvimento Infantil/fisiologia , Cognição/fisiologia , Eletroencefalografia , Estimulação Acústica , Ritmo alfa , Criança , Pré-Escolar , Feminino , Humanos , Inteligência/fisiologia , Masculino , Testes Neuropsicológicos , Estimulação Luminosa , Ritmo Teta , GêmeosAssuntos
Atenção/fisiologia , Recém-Nascido Prematuro/fisiologia , Ritmo Teta , Feminino , Humanos , Lactente , Recém-Nascido , Masculino , Nascimento PrematuroAssuntos
Individualidade , Temperamento/fisiologia , Distribuição de Qui-Quadrado , Análise Fatorial , Família/psicologia , Genética Comportamental , Genótipo , Humanos , Lactente , Fenótipo , Meio Social , Inquéritos e Questionários , Gêmeos Dizigóticos/genética , Gêmeos Dizigóticos/psicologia , Gêmeos Monozigóticos/genética , Gêmeos Monozigóticos/psicologiaAssuntos
Individualidade , Temperamento , Estudos de Avaliação como Assunto , Análise Fatorial , Humanos , LactenteRESUMO
The studies were made on the interaction of alpha-chymotrypsin with a series of cyclopeptides cyclo(-L-leucyl-L-tyrosyl-glycyln-), n=4, 6 and 8 (I, II and III respectively), and cyclo(-L-leucyl-L-tryosyl-beta-aminovalero-yl2-) (IV). Compounds I and IV are resistant to enzyme action whereas cyclopeptides II and III proved to be the substrates, their kinetic constants being Km=15.4 and 13.2 mM and kcat=0.54 and 9.53 sec-1 respectively. The binding capacity of cyclopeptides I-IV is evaluated by their competitive inhibition of alpha-chymotrypsin catalyzed hydrolysis of N-acetyl-L-tyrosine methyl ester.
