Demographic and clinical profile of craniofacial clefts at comprehensive rehabilitation service in Uganda

Background: The true incidence of Craniofacial cleft (CFC) is unknown because of their scarcity and because of the difficulty in recognizing sometimes subtle physical findings in mild malformations. Craniofacial anomalies in the African population are reported infrequently. Aim: To contribute to the general literature on rare CFC in Uganda and Africa. Methods: we conducted a retrospective search of patient data over the period 2005 to May 2017 in the unit of plastic surgery of CoRSU (Comprehensive Rehabilitation Service in Uganda) hospital, a tertiary hospital in Uganda. Patient with a diagnosis of CFC were picked out. Sixty-six patient's files with clinical diagnosis of CFC including their clinical photographs were found. Frequency data was generated and a frequency distribution table with the observed data was constructed. Results: Sex distribution showed no significant difference between male and female (1:1,2);the age on admission ranged from 1 day to 83 years; according to the laterality of the cleft, unilateral CFC (left or right side) are more common than midline clefts (Tessier 0; 14; 0,14;30); however, according to the clinical type, Tessier cleft (TC) 0 is the most common TC in our series and is associated with holoprosencephaly. Fifty percent of CFC in our series are syndromic. TC 7 are common in male and have a bilateral predilection. Conclusion: CFC are a rare set of malformations for which there is a paucity of literature. There is a need to conduct a study with a larger series including CT-Scan in order to analyze more accurate clinical diagnosis

Les Fentes labio-palatines non syndromiques a l'est de la Republique Democratique du Congo. Aspects epidemiologiques; cliniques et therapeutiques

But de l'etude:decrire le profil epidemiologique; clinique et therapeutique des fentes labio-palatines observees a l'Est de la RDC (Republique Democratique du Congo) de novembre 2010 a mars 2011 soit durant 5 mois.Malades et methode:c'est une etude descriptive transversale realisee au Centre Hospitalier 'Doctors on Call for Service (DOCS)' de Goma en RDC et qui a porte sur 160 cas de fentes labiales et/ou palatines selectionnees au moyen d'un echantillonnage non probabiliste; a tout venant et operees au cours de cette meme periode. Le traitement des donnees a ete facilite par l'usage du progiciel SPSS 17.0. Les resultats ont ete valides par le test de Khi-carre au seuil de 0;05.Resultats:la majorite de nos patients (76;3) sont venus des milieux ruraux et ont a la consultation et a l'operation un age moyen de 15;19 ans avec comme extreme trois mois et 62 ans; dont 47;5 des cas sont operes apres l'age de 10 ans. Le manque de moyen financier (58;7 des cas) suivi par le manque d'information (22;5) constituent les principaux motifs du retard a la consultation et a l'operation. Les deux sexes sont concernes avec une predominance masculine (60;6). La scolarisation de ces patients est significativement plus faible pour les sujets feminins (54;5 non scolarisees) par rapport aux sujets masculins (45;5 non scolarises) (x2=15;417; ddl=3; p=0;001). Il y a plus d'hommes maries que d'hommes celibataires ayant atteint la maturite ; l'inverse est observe chez les sujets feminins (x2=1;137; ddl=2; p=0;556).La fente labiale isolee est le type le plus frequent (97;5); elle est unilaterale dans 81;9 des cas; incomplete (50;1) et siegeant a gauche (49;9)(x2=10;055 ;ddl=9 ;p=0;346). Aucun antecedent heredo-collateral de malformation congenitale n'a ete enregistre chez 96;3 des cas.La technique de Millard modifiee a ete utilisee dans 94;2 des cas pour corriger la fente labiale et toutes les fentes palatines ont ete corrigees par la technique de Von Langenbeck. L'anesthesie generale avec intubation orotracheale (IOT) a ete utilisee chez tous les enfants d'age inferieur ou egal a cinq ans alors que l'anesthesie locale a ete utilisee chez 96;4 des patients ages de 16 ans et plus (x2=152;182; ddl=6; p=0;000). Nous n'avons enregistre aucune complication postoperatoire dans 98;8 des cas et la duree moyenne d'hospitalisation est de deux jours

[The epidemiological approach of clefts lip and palate in the eastern of Democratic Republic of Congo]. / Les fentes labiopalatines à l'est de la République Démocratique du Congo. Aspects épidémiologiques.

OBJECTIVE: This study aims to present the epidemiological profile of clefts lip/palate observed in the eastern of Democratic Republic of Congo (DRC) from January 2002 to May 2004, period of civil wars. METHOD: It is a retrospective study realized at Doctors on Call for service Learning Center (DOCS LC) in Goma/DRC concerning 89 cases of cleft lip/palate operated during the same period. The data processing was facilitated by the software package SPSS 17.0 installed in the IT center of DOCS. RESULTS: The average age of the consultation is 9.9 years with extreme of zero and 42 years. Both sexes are concerned: 50.6% of male and 49.4% of female. The more cleft extends from the superior lip to the palate through the alveolus, the more the frequency of the various types of clefts lips/palate decreases: 59.6% (simple clefts lip), 37.1% (labio-alveolar clefts), and 2.2% (cleft palate). The left incomplete cleft lip variety represents 33.7% of all varieties. Most of clefts lips/palate come from the first to the fifth pregnancy with a peak of frequency (19.1%) in the second pregnancy. No family history about congenital deformation was found from 97% of our patients. CONCLUSION: The epidemiology of cleft lip/palate in our area would be more connected to environmental factors than genetics: no family history of congenital deformation was seen for most of our patients during this period of civil war.