[The effect of applying clinical organizational telemedicine technology management of anti-tuberculous care on dynamics of tuberculosis morbidity and mortality].

The tuberculosis is the most important medical and social problem among globally dangerous epidemiological phenomena. the tuberculosis ranks 9th place in the structure of mortality and disability of population and 1st place among causes of death from single infectious agent.The purpose of the study was to analyze dynamics of total morbidity and mortality because of tuberculosis against the background of the implementation of telemedicine clinical organizational technology in phthisiology care 2007-2021.The official Regional and Federal data of Rosstat for 2007-2021 were used. The indicators of total morbidity and mortality of population caused by tuberculosis in the Sverdlovsk Oblast were established. The research methods were content analysis, dynamic series analysis, graphical analysis, statistical differences analysis.In the Sverdlovsk Oblast, the morbidity and mortality of tuberculosis exceeded national average indicators by 1.2-1.5 times. In 2007-2021, as a result of implementation of clinical organizational telemedicine technology in managing phthisiology care, total morbidity and mortality of population caused by tuberculosis decreased up to 2.275 and 2.97 times respectively. The rate of decrease of analyzed epidemiological indicators generally correlated with national average data with statistical validity of difference t≥2.In regions with unfavorable epidemiological indicators of tuberculosis, application of innovative technologies in management of clinical organizational processes is required. The development and implementation of clinical organizational telemedicine technology for managing regional phthisiology care contributes to significant reduction of morbidity and mortality of tuberculosis and optimizes sanitary and epidemiological well-being.

Forecasting Trends in the Tuberculosis Epidemic Situation in the Region of the Russian Federation by Dynamic Simulation Model.

The spread of a new coronavirus infection in the last two years together with HIV infection preserves and even increases the potential for the spread of tuberculosis in the world. Sverdlovsk oblast (SO) of Russian Federation is the region with high levels of HIV and tuberculosis (TB). The search for new methods of forecasting of the future epidemic situation for tuberculosis has become particularly relevant. The aim was to develop an effective method for predicting the epidemic situation of tuberculosis using an artificial intelligence (AI) method in the format of a dynamic simulation model based on AI technologies. Statistical data was loaded from the state statistical reporting on TB patients for the period 2007-2017. The parameters were controlled through a system of inequalities. The proposed SDM made it possible to identify and reliably calculate trends of TB epidemiological indicators. Comparison of the predicted values made in 2017 with the actual values of 2018-2021 revealed a reliable coincidence of the trend of movement of TB epidemiological indicators in the region, the maximum deviation was no more than 14.82%. The forecast results obtained with SDM are quite suitable for practical use. Especially, in operational resource planning of measures to counteract the spread of tuberculosis at the regional level.

Control of sub-terahertz gyrotron frequency by modulation-anode voltage: Comparison of theoretical and experimental results.

This paper presents a comparison of simple self-consistent theory data and experimental results aimed to study the influence of the anode voltage on the frequency of the subterahertz gyrotron with the goal of frequency stabilization. Numerical simulations of the electron beam formation and beam-wave interaction in a 0.26 THz gyrotron are performed. The experimental dependence of the gyrotron frequency tuning on mod-anode voltage is in agreement with theoretical predictions.

First experimental tests of powerful 250 GHz gyrotron for future fusion research and collective Thomson scattering diagnostics.

A 250 GHz continuous-wave (CW) gyrotron has been developed at the IAP RAS jointly with GYCOM Ltd., as a prototype of the microwave source for the envisaged prospective nuclear fusion power plants (DEMO). The main applications of such a tube are electron cyclotron resonance heating and electron cyclotron resonance current drive of magnetically confined plasma as well as its diagnostics based on collective Thomson scattering in various reactors for controlled thermonuclear fusion (e.g., tokamaks and stellarators). The results of the preliminary experimental tests in a pulsed mode of operation are presented. The microwave power of up to 330 kW with an efficiency of 30% without collector depression was obtained. At an accelerating voltage of 55 kV and an electron beam current of 12.5 A (which corresponds to the design parameters for CW operation), the measured output power was about 200 kW. The TEM00 mode content evaluated at the tube output is not less than 98.6%.

Experimental tests of a 263 GHz gyrotron for spectroscopic applications and diagnostics of various media.

A 263 GHz continuous-wave (CW) gyrotron was developed at the IAP RAS for future applications as a microwave power source in Dynamic Nuclear Polarization / Nuclear magnetic resonance (DNP/NMR) spectrometers. A new experimental facility with a computerized control was built to test this and subsequent gyrotrons. We obtained the maximum CW power up to 1 kW in the 15 kV/0.4 A operation regime. The power about 10 W, which is sufficient for many spectroscopic applications, was realized in the low current 14 kV/0.02 A regime. The possibility of frequency tuning by variation of the coolant temperature about 4 MHz/1 °C was demonstrated. The spectral width of the gyrotron radiation was about 10(-6).