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Fiziol Zh (1994) ; 42(1-2): 47-52, 1996.
Artigo em Ucraniano | MEDLINE | ID: mdl-8991715

RESUMO

In children of 4-7 years old with bronchial asthma (BA) has been studied the values of lipid peroxidation, antioxidant status and some others in blood plasma and erythrocytes without and with the use of new drug Lipin. It was shown that in children with BA the malondialdehyde concentration increased, the superoxydedismutase activity decreased, the NAD concentration increased, and the ratio of superoxidedismutase/malondialdehyde greatly decreased in comparison with normal children. The use of Lipin led to diminuation of lipid peroxidation, to marked increase of superoxidedismutase activity, to decrease of NAD concentration, and to significant increase of superoxidedismutase/malondialdehyde ratio. These results were indicated on the expressed antioxidant properties of Lipin in children's with BA.


Assuntos
Anti-Infecciosos/administração & dosagem , Antioxidantes/administração & dosagem , Asma/tratamento farmacológico , Administração por Inalação , Asma/sangue , Criança , Pré-Escolar , Portadores de Fármacos , Avaliação de Medicamentos , Membrana Eritrocítica/efeitos dos fármacos , Membrana Eritrocítica/metabolismo , Humanos , Peroxidação de Lipídeos/efeitos dos fármacos , Lipossomos , Compostos Orgânicos
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