RESUMO
64 patients with infectious-allergic bronchial asthma (IABA) were examined. 20 of them were co-administered paspat, 24 patients additionally received prodigiosan, 20 patients constituted control group and were given conventional treatment. Patients of all the groups were comparable in age, state of immunological reactivity of the body and severity of the disease. Immunomodulatory effect of the drugs, mainly of paspat, not only resulted in normalization of functional properties of granulocytes but also promoted liquidation of quantitative and functional IABA-conditioned immunodeficiency on the part of T- and B-lymphocytes, thus increasing effectiveness of the treatment in the whole.
Assuntos
Antígenos de Bactérias/uso terapêutico , Asma/terapia , Prodigiozan/uso terapêutico , Adolescente , Adulto , Asma/imunologia , Avaliação de Medicamentos , Quimioterapia Combinada , Feminino , Humanos , Imunidade Celular/efeitos dos fármacos , Masculino , Pessoa de Meia-IdadeRESUMO
A study of 73 patients suffering of asthma bronchiale with postloading bronchospasm and 20 without bronchospasm indicates that most pronounced bronchoconstriction after physical loads appears on the 15-20 minute in atopic asthma and asthma of physical exertion and by the 5-10 min. in infectious-allergic form of the disease. It is recommended to use MEF75, MEF50 and MEF25 as a diagnostic criterion of postloading bronchospasm.