[COMPARATIVE ESTIMATION OF THE SURGICAL TREATMENT RESULTS IN CYSTIC MENINGIOMAS OF THE BRAIN, USING THE STANDARD METHODS AND NEW TECHNOLOGIES].

The results of surgical treatment of 54 patients, suffering the brain cystic meningiomas of various localization, were analyzed. The patients were operated on in universal conditions by neurosurgeons of one operative team, of them 24 ­ using new technologies. Wide application of new technologies in surgery of the brain cystic meningiomas have permitted to reduce the surgical intervention invasiveness essentially, and, as a consequence, to reduce trustworthily the operation time essentially, as well as the intraoperative blood loss severity.

[Role of apolipoprotein B and lipoprotein lipase gene polymorphism in variability of serum lipid levels]. / Rol' polimorfizma genov apolipoproteina B i lipazy lipoproteinov v izmenchivosti urovnia lipidov plazmy krovi.

The serum lipid level is determined by the complex interaction of genetic and environmental factors. The genetic component of this system includes apolipoprotein B (apoB) and lipoprotein lipase (LPL) genes. Three RFLP markers (XbaI, MspI, EcoRI) in the apoB gene and PvuII-RFLP in the LPL gene were genotypes and five lipid traits (fasting plasma levels of total cholesterol, triglycerides, HDL-, LDL-, and VLDL- cholesterol) were measured in 122 unrelated individuals without clinical signs of cardiovascular disease. Several alleles and genotypes which were associated with significant effects on cholesterol, triglycerides, and LDL-cholesterol levels were identified. Analysis of intragenotypic variance and multivariate measures of the mean values of lipid concentrations indicate that apoB gene variation may contribute both to the level and variability of plasma lipids.