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Genet Mol Res ; 14(1): 1096-105, 2015 Feb 06.
Artigo em Inglês | MEDLINE | ID: mdl-25730049

RESUMO

Mature embryos in tissue cultures are advantageous because of their abundance and rapid germination, which reduces genomic instability problems. In this study, 2-day-old isolated mature barley embryos were infected with 2 Agrobacterium hypervirulent strains (AGL1 and EHA105), followed by a 3-day period of co-cultivation in the presence of L-cystein amino acid. Chimeric expression of the b-glucuronidase gene (gusA) directed by a viral promoter of strawberry vein banding virus was observed in coleoptile epidermal cells and seminal roots in 5-day-old germinated seedlings. In addition to varying infectivity patterns in different strains, there was a higher ratio of transient b-glucuronidase expression in developing coleoptiles than in embryonic roots, indicating the high competency of shoot apical meristem cells in the mature embryo. A total of 548 explants were transformed and 156 plants developed to maturity on G418 media after 18-25 days. We detected transgenes in 74% of the screened plant leaves by polymerase chain reaction, and 49% of these expressed neomycin phosphotransferase II gene following AGL1 transformation. Ten randomly selected T0 transformants were analyzed using thermal asymmetric interlaced polymerase chain reaction and 24 fragments ranged between 200-600 base pairs were sequenced. Three of the sequences flanked with transferred-DNA showed high similarity to coding regions of the barley genome, including alpha tubulin5, homeobox 1, and mitochondrial 16S genes. We observed 70-200-base pair filler sequences only in the coding regions of barley in this study.


Assuntos
Hordeum/genética , Plantas Geneticamente Modificadas/genética , Plântula/genética , Transformação Genética , Agrobacterium tumefaciens/genética , Vetores Genéticos , Genoma de Planta , Genômica , Germinação/genética , Hordeum/embriologia , Hordeum/crescimento & desenvolvimento , Canamicina Quinase/genética , Meristema/embriologia , Meristema/genética , Meristema/crescimento & desenvolvimento , Plantas Geneticamente Modificadas/embriologia , Plantas Geneticamente Modificadas/crescimento & desenvolvimento , Plântula/embriologia , Plântula/crescimento & desenvolvimento , Sementes/genética , Sementes/crescimento & desenvolvimento , Transgenes
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