1.
Acta Crystallogr E Crystallogr Commun
; 78(Pt 1): 29-32, 2022 Jan 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35079418
RESUMO
A new synthesis of the title compound, C19H21NO2, was developed with good yield and purity using the reaction of 4-hy-droxy-3-methyl-2-butanone, benzaldehyde and ammonium acetate in glacial acetic acid as a solvent. The central piperidine ring adopts a chair conformation, and its least-squares basal plane forms dihedral angles of 85.71â (11) and 77.27â (11)° with the terminal aromatic rings. In the crystal, the mol-ecules are linked by O-Hâ¯O and C-Hâ¯O hydrogen bonds into double ribbons. The Hirshfeld surface analysis shows that the most important contributions are from Hâ¯H (68%), Câ¯H/Hâ¯C (19%) and Oâ¯H/Hâ¯O (12%) inter-actions.