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1.
J Pharm Bioallied Sci ; 12(Suppl 1): S78-S85, 2020 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-33149435

RESUMO

INTRODUCTION: The relationship between chronic periodontitis and type 2 diabetes mellitus (DM) is bidirectional. Halitosis or oral malodor has an effect on psychological and social life of persons, and is seen in individuals with diabetes. AIMS AND OBJECTIVES: The aim of this study was to find out the effect of phase I therapy on the clinical parameters, volatile sulfur compound (VSC) levels, and random blood sugar (RBS) levels in chronic periodontitis patients with diagnosed DM. MATERIALS AND METHODS: Our study included 80 patients with diabetes and chronic periodontitis. We collected subgingival plaque samples at 1 week and 1 month after scaling and root planing. The parameters measured were probing pocket depth and clinical attachment level for all the teeth at four sites per each tooth. RBS levels were recorded for all the patients. Malodor was measured with Tanita Breath Checker (Tanita India Private Limited, Mumbai, Maharashtra, India). RESULTS: We found a statistically significant reduction in clinical parameter levels, VSC levels, and N-benzoyl-DL-arginine-2-naphthylamide (BANA) levels in both the groups from baseline to 4 weeks with highest levels in diabetic chronic generalized periodontitis (CGP) and lowest in nondiabetic CGP at baseline. The mean intergroup comparison of BANA levels was statistically significant at all intervals of time between the two the groups. CONCLUSION: There is a significant correlation observed between oral malodor levels, RBS, and clinical parameters in the diabetic group.

2.
J Contemp Dent Pract ; 21(6): 604-608, 2020 Jun 01.
Artigo em Inglês | MEDLINE | ID: mdl-33025926

RESUMO

AIM: This study aims to evaluate and compare the efficacy of auto-control syringe (ACS) and insulin syringe (IS) for palatal local anesthesia administration in children. MATERIALS AND METHODS: The study was a double-blind, randomized, and crossover trial, comprising 80 children requiring palatal anesthesia bilaterally (total 160 injections). Palatal anesthesia on one side was delivered with ACS in one appointment and contralaterally with IS in the second appointment. One-week washout period was given between first and second appointments. Each child acted as his own control. Each injection technique subjective and objective pain scores were measured twice (during needle prick and during actual deposition of local anesthesia). Subjective and objective evaluation of pain was measured with Wong-Baker FACES pain rating scale (WB-FPS) and the face, leg, activity, cry, and consolability scale (FLACC), respectively. After concluding second appointment, child was asked about their preference between both ACS and IS. Statistical evaluation was performed using Chi-square test. RESULTS: Child reported less pain score for needle prick with IS as opposed to ACS (p value = 0.000416). There was no significant difference between dentist-reported pain scores between any group for both needle prick and local anesthesia administration. There is no significant difference between child reported pain score during administration of local anesthesia between two groups. Irrespective of pain scores, most of the children (96.5%) preferred IS. CONCLUSION: For palatal local anesthesia administration in children, both IS and auto-controlled syringe have similar efficacy. CLINICAL SIGNIFICANCE: Insulin syringe can serve as an economical alternative to the expensive auto-controlled syringe for palatal injections in children.


Assuntos
Anestesia Dentária , Anestésicos Locais , Insulinas , Seringas , Anestesia Dentária/métodos , Anestésicos Locais/administração & dosagem , Criança , Estudos Cross-Over , Humanos , Medição da Dor
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