1.
Org Lett
; 13(21): 5796-9, 2011 Nov 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21992717
RESUMO
Conjugate addition of arylboronates to α,ß-unsaturated ketones may be catalyzed by chiral binaphthols with enantioselectivities of up to 99:1. Best results were observed with 3,3'-dichloro-BINOL. This chemistry was applied to syntheses of intermediates for syntheses of (+)-indatraline and (+)-tolterodine.