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1.
PLoS One ; 18(4): e0282183, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37053231

RESUMO

It is widely acknowledged that social network support plays an important role in the quality of life and illness management of breast cancer survivors. However, the factors and processes that enable and sustain such support are less well understood. This paper reports baseline findings from a prospective UK national cohort of 1,202 women with breast cancer (aged <50 years at diagnosis), recruited before starting treatment, conducted in 2016-2019. Descriptive, univariate and multivariate regression analyses explored associations between the individual, and network member characteristics, and the type of support provided. Social network members provided a substantial level of illness-related, practical and emotional support. Highest contribution was provided by friends, followed by close family members. The social network members of women who did not have a partner provided a higher level of support than those in networks with a partner. Women without higher education were more reliant on close family members than those with higher education, and this was more so for women without a partner. Women with higher education without a partner were more reliant on friends and were overall best supported. Women without higher education who did not have a partner were overall least well supported. They had much smaller networks, were highly reliant on close family members, and on high level contributions from all network members. There is a need to develop network-based interventions to support people with a cancer diagnosis, prioritising support for the groups identified as most at risk. Interventions that support engagement with existing network members during treatment, and those that help extend such networks after treatment, are likely to be of benefit. A network perspective can help to develop tailored support and interventions by recognising the interactions between network and individual level processes.


Assuntos
Neoplasias da Mama , Autogestão , Humanos , Feminino , Neoplasias da Mama/diagnóstico , Neoplasias da Mama/terapia , Neoplasias da Mama/psicologia , Qualidade de Vida/psicologia , Estudos Prospectivos , Apoio Social , Rede Social
2.
J Cosmet Dermatol ; 22(1): 79-88, 2023 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-35384270

RESUMO

As the desire and popularity of a tanned appearance continues, the social effects of UV-free tanning are becoming more important. Dihydroxyacetone (DHA) has seen extensive use as the main tanning agent in sunless tanners. The DHA-induced tan is a result of brown melanoidins formed by a non-enzymatic Maillard reaction between DHA and amino acid species found in the stratum corneum. DHA, thereby, provides a safer route to a tanned appearance compared with exposure to ultraviolet radiation. However, DHA is a highly reactive molecule, posing a multitude of challenges for potential product formulations. With their increased use, the safety considerations of topically applied DHA tanners have been investigated. Many different vehicles have been used for topical delivery of DHA, and they are becoming increasingly multifunctional. This review provides a holistic overview of dihydroxyacetone sunless tanning products.


Assuntos
Di-Hidroxiacetona , Raios Ultravioleta , Humanos , Di-Hidroxiacetona/farmacologia , Raios Ultravioleta/efeitos adversos , Epiderme , Aminoácidos , Composição de Medicamentos
3.
J Pastoral Care Counsel ; 77(2): 113-122, 2023 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-36451598

RESUMO

An expert panel consisting of six mental health chaplains from several European countries was convened to ascertain the specific contribution of mental health chaplains to suicide prevention, and to generate good practices for suicide prevention. Three themes emerged: (1) the importance of timing; (2) fundamental attitudes of the chaplain towards the patient, and (3) appropriate interventions.


Assuntos
Serviço Religioso no Hospital , Assistência Religiosa , Suicídio , Humanos , Clero/psicologia , Saúde Mental , Atitude
4.
J Sci Med Sport ; 23(10): 985-990, 2020 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-32284293

RESUMO

OBJECTIVES: To determine the influence of tracking marker locations on wrist kinematics during free movements and the golf swing, with the intention of recommending a solution that generates meaningful three-dimensional wrist kinematics. DESIGN: Repeated measures. METHODS: Six participants performed free movements of flexion/extension, radial/ulnar deviation and forearm supination/pronation, with a further sixteen participants performing golf drives. A passive motion capture system tracked four different marker sets located on participants' hand and forearm segments. Variables of peak angle and range of motion were used to compare marker sets during free movements and angles at the top of the backswing and impact were compared during the golf swing. RESULTS: Wrist marker set had a large (η2≥0.557) and often significant (p≤0.051) effect on the variables measured during free movements, and a mixed (η2≥0.108, p≤0.198) effect on wrist angles during the golf swing. Wrist axial rotation range of motion during free forearm supination/pronation revealed the greatest difference between marker sets (∼42°). The large values generated by two of the marker sets for this rotation appeared to influence the values of flexion/extension and radial/ulnar deviation during the golf swing. CONCLUSIONS: The location of markers used to measure wrist kinematics can have a large effect on the angles generated. A solution of two markers located at the distal end of the forearm and one at the proximal, appears to minimise values of wrist axial rotation during free forearm supination/pronation and, consequently, produce more meaningful three-dimensional wrist kinematics.


Assuntos
Antebraço/fisiologia , Golfe/fisiologia , Movimento/fisiologia , Amplitude de Movimento Articular/fisiologia , Articulação do Punho/fisiologia , Adulto , Fenômenos Biomecânicos , Humanos , Masculino , Análise e Desempenho de Tarefas , Adulto Jovem
5.
Polymers (Basel) ; 11(6)2019 Jun 12.
Artigo em Inglês | MEDLINE | ID: mdl-31212855

RESUMO

Desire to accurately predict the deformation behaviour throughout industrial forming processes, such as thermoforming and stretch blow moulding, has led to the development of mathematical models of material behaviour, with the ultimate aim of embedding into forming simulations enabling process and product optimization. Through the use of modern material characterisation techniques, biaxial data obtained at conditions comparable to the thermoforming process was used to calibrate the Buckley material model to the observed non-linear viscoelastic stress/strain behaviour. The material model was modified to account for the inherent anisotropy observed between the principal directions through the inclusion of a Holazapfel-Gasser-Ogden hyperelastic element. Variations in the post-yield drop in stress values associated with deformation rate and specimen temperature below the glass transition were observable, and facilitated in the modified model through time-temperature superposition creating a linear relationship capable of accurately modelling this change in yield stress behaviour. The modelling of the region of observed flow stress noted when above the glass transition temperature was also facilitated through adoption of the same principal. Comparison of the material model prediction was in excellent agreement with experiments at strain rates and temperatures of 1-16 s-1 and 130-155 °C respectively, for equal-biaxial mode of deformation. Temperature dependency of the material model was well replicated with across the broad temperature range in principal directions, at the reference strain rate of 1 s-1. When concerning larger rates of deformation, minimum and maximum average error levels of 6.20% and 10.77% were noted. The formulation, and appropriate characterization, of the modified Buckley material model allows for a stable basis in which future implementation into representative forming simulations of poly-aryl-ether-ketones, poly(ether-ether-ketone) (PEEK) and many other post-yield anisotropic polymers.

6.
RSC Adv ; 9(67): 39143-39146, 2019 Nov 27.
Artigo em Inglês | MEDLINE | ID: mdl-35540660

RESUMO

A reactive ink (Ink 1) containing Ti(OPri)4 in PriOH with dimethoxyethan as a kinetic stabiliser deposits TiO2 by inkjet printing. A hybrid ink (Ink 2) consists of Ink 1 with the addition of anatase NPs, which act as seeds for the formation of anatase TiO2 at 200 °C. Printing of anatase on PET is also reported.

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