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2.
Diagn Cytopathol ; 39(2): 101-4, 2011 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-20146303

RESUMO

Malignant cells of prostatic adenocarcinoma are rarely identified in urine. In most cases, this finding is associated with high stage tumor. Numerous descriptions of the morphology of prostatic adenocarcinoma have been reported using cytocentrifugated specimens. However, no specific morphologic description of prostatic adenocarcinoma in urine using liquid-based cytology has been previously described. Four cases of prostatic adenocarcinoma in urine using ThinPrep® liquid-based preparations were identified between 2002 and 2009 at the University of Wisconsin Hospital and Clinics. Three patients had either high stage tumor or metastatic disease at the time of diagnosis, while the remaining patient had low stage tumor. The morphology of each case was evaluated with specific attention to cell size, nuclear characteristics, nuclear to cytoplasmic ratio, and cytoplasmic characteristics. The resulting key features for prostatic adenocarcinoma in urine are clustering, increased nuclear to cytoplasmic ratio, and prominent nucleoli. Though typically the presence of prostatic adenocarcinoma in urine implies high stage tumor, cells of lower stage tumors may be seen in urine as well.


Assuntos
Adenocarcinoma/patologia , Adenocarcinoma/urina , Neoplasias da Próstata/patologia , Neoplasias da Próstata/urina , Urina/citologia , Citodiagnóstico , Técnicas Citológicas , Humanos , Masculino , Estadiamento de Neoplasias , Hiperplasia Prostática/patologia
3.
S D Med ; 63(4): 123-5, 2010 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-20397374

RESUMO

Synchronous presentation of breast cancer and lymphoma is extremely rare. Few cases are reported in the literature. We describe a case of invasive ductal carcinoma of the breast with micrometastasis to a non-sentinel lymph node and subsequent incidental finding of a low-grade follicular lymphoma in an axillary node of a 52-year-old woman. The characteristic immunohistochemical profile of the lymphoma is described.


Assuntos
Neoplasias da Mama/patologia , Carcinoma Ductal de Mama/patologia , Linfoma Folicular/patologia , Neoplasias Primárias Múltiplas/patologia , Antígenos CD20/metabolismo , Biópsia por Agulha , Feminino , Humanos , Imuno-Histoquímica , Linfonodos/patologia , Linfócitos/metabolismo , Pessoa de Meia-Idade
4.
S D Med ; 60(10): 401-3, 2007 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-18019775

RESUMO

Mature cystic teratoma is a common benign adnexal tumor in females. We describe a 43-year-old female with a 10 cm left ovarian mature cystic teratoma with the rare finding of squamous cell carcinoma. The clinical evaluation with ultrasound and serologic markers is discussed. Treatment typically consists of surgical resection with adjuvant chemotherapy using platinum-based agents. Prognosis is extremely poor in most cases.


Assuntos
Neoplasias de Células Escamosas/patologia , Neoplasias Ovarianas/patologia , Teratoma/patologia , Adulto , Protocolos de Quimioterapia Combinada Antineoplásica/uso terapêutico , Terapia Combinada , Evolução Fatal , Feminino , Humanos , Histerectomia , Metástase Neoplásica , Neoplasias de Células Escamosas/terapia , Neoplasias Ovarianas/terapia , Teratoma/terapia
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