[The body's nonspecific resistance factors in a localized experimental infection caused by Bacteroides]. / Sostoianie faktorov nespetsificheskoi rezistentnosti organizma v usloviiakh lokalizovannoi éksperimental'noi infektsii, vyzvannoi bakteroidami.

Under local experimental infection induced by bacteroides of Fragilis group the factors of nonspecific organism resistance take an active part in the inflammation process. Phase changes of the state of monocytic-phagocytic and complement systems were observed. Peripheral blood leukocyte phagocytic activity decreased at the primary stage, then followed the complement activation by the alternative pathway mainly. The increase of phagocytic and metabolic activities of those phagocytes taking part in the inflammation, the complement at this stage is activated due to the classical pathway while being at the stage of clinic manifestation. Levels of antibody titres are also increasing.

[Non-clostridial anaerobes in the etiopathogenesis of perivesical cholangiogenic abscesses of the liver]. / Neklostridial'nye anaéroby v étiopatogeneze perivezikal'nykh kolangiogennykh abstsessov pecheni.

The authors had under observation 318 patients who were subjected to operation and suffered from various inflammatory diseases of the bile tract; perivesical and cholangiogenic abscesses of the liver were found in 33 of them. Bacteriological tests of the contents of the abscesses demonstrated most frequently the presence of Bacteroides fragilis as a monoculture in cholangiogenic abscesses and associations of anaerobic and aerobic bacteria in perivesical abscesses. Early operation with obligatory consideration for the anaerobic component of the microflora is recommended.

[Surgical tactics in destructive cholecystitis]. / Khirurgicheskaia taktika pri destruktivnom kholetsistite.

Bacteriological examinations of anaerobic and aerobic microflora of the bile, tissues of the gallbladder wall in 67 patients operated on with destructive cholecystitis have shown that surgical interventions should be performed within the first hours after admission to the hospital and must include special methods of purposeful antibacterial therapy during operation and in the postoperative period.

[Non-clostridial anaerobic infection in complicated cholecystitis]. / Neklostridial'naia anaerobnaia infektsiia pri oslozhnennom kholetsistite.

Results of bacteriological investigations and treatment of 112 patients with complicated forms of acute cholecystitis are described. It was found that in complicated forms of acute cholecystitis an important part was played by associations of bacteria among which neclostridial anaerobes were of leading importance responsible for the aggravation of the inflammatory process and course of the postoperative period. The intracholedochal antibacterial therapy with Dioxidin in combination with antibiotics is thought to be expedient.