[Effect of adaptation to high altitude on the state of electric cardiac stability and lipid peroxidation during catecholamine cardionecrosis in rats]. / Vliianie adaptatsii k vysokogor'iu na sostoianie élektricheskoi stabil'nosti serdtsa i perekisnogo okisleniia lipidov pri katekholaminovom kardionekroze u krys.

The change of electric cardiac stability parameters and LP in catecholamine cardio necrosis in rats simulated by prolonged injection of increasing doses of noradrenaline was studied in this work. It was established that noradrenaline injection in low-altitude (760 m) and high-altitude (3200 m) is accompanied by hypertrophy, microcirculation disturbances, ischemia and cardiomyocytes necrosis, ECS decrease, LP activation and decrease of enzymatic activity of antioxidant defense. ECS of animals adapted to high-altitude decreased less and their LP processes were more active with preservation of enzymatic activity of antioxidant defense.

[Changes in hemocoagulation in altitude-sensitive animals with catecholamine cardiac necrosis]. / Izmenenie gemokoaguliatsii pri katekholaminovom kardionekroze u ne adaptirovannykh k vysokogor'iu zhivotnykh.

Norepinephrine injected to adult Wistar rats at low altitude (760 m) and high altitude (3200 m) induced hypertrophy and focal myocardial necrosis ascribed to, specifically, changes in blood hypercoagulation. More pronounced changes developed in altitude-sensitive animals in the mountains.