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Mol Med Rep ; 4(5): 919-22, 2011.
Artigo em Inglês | MEDLINE | ID: mdl-21667028

RESUMO

The giant jellyfish Nemopilema nomurai (reaching sizes of up to 2 m diameter and 150 kg), which forms dense blooms, has caused extensive damage to fisheries by overloading trawl nets, while its toxic nematocysts cause dermatological symptoms. Giant jellyfish are currently discarded on the grounds of pest control. However, the giant jellyfish is considered to be edible and is part of Chinese cuisine. Therefore, we investigated whether any benefits for human health may be derived from consumption of the jellyfish in order to formulate medicated diets. Antioxidant activity of Nemopilema nomurai was measured using the oxygen radical absorbance capacity (ORAC) and hydroxyl radical averting capacity (HORAC) methods. Based on the results, the ORAC value of the giant jellyfish freeze-dried sample was 541 µmol trolox equivalent (TE)/100 g and the HORAC value was 3,687 µmol gallic acid equivalent (GAE)/100 g. On the other hand, the IC50 value of hydroxyl radical scavenging activity measured by using the electron spin resonance method was 3.3%. In conclusion, the results suggest that the freeze-dried powder of the giant jellyfish Nemopilema nomurai is a potentially beneficial food for humans.


Assuntos
Antioxidantes/farmacologia , Radical Hidroxila/metabolismo , Oxigênio/metabolismo , Cifozoários/química , Absorção/efeitos dos fármacos , Animais , Sequestradores de Radicais Livres/farmacologia , Alimento Funcional , Humanos , Interações Hidrofóbicas e Hidrofílicas , Radical Hidroxila/química , Concentração Inibidora 50
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