RESUMO
The hydrodynamic properties of the blood plasma flow in smallest microvessels have been investigated. It has been shown that velocity distribution in such flows essentially differs from the Poseuille flow. The interrelations between the optical parameters and hydrodynamic characteristics of blood microflow have been analyzed. A new method for in vivo measurement of blood plasma rate in small microvessels is proposed, which uses in vivo microscopy in combination with speckle microscopy.
Assuntos
Velocidade do Fluxo Sanguíneo/fisiologia , Modelos Cardiovasculares , Animais , Capilares/fisiologia , Humanos , Microscopia/métodosRESUMO
The role of temporal coherence at photodynamic action of light on living cells was investigated. A mathematical model describing the interaction of low-coherent speckles with bacterial cells was suggested and its parameters were determined based on experimental data. The interrelation between the life time of dynamic optical speckles and the degree of photodestruction of illuminated cells was established by computer simulations. The conditions were determined under which the photoinactivation of cells of the vaccine strain of the causative agent of F. tularensis 15 NIIEG occurs.
Assuntos
Simulação por Computador , Francisella tularensis/crescimento & desenvolvimento , Luz , Modelos Teóricos , Francisella tularensis/efeitos da radiaçãoRESUMO
Lymph flow as measured with biomicroscopic and speckle-interferometrical techniques was very unstable and its rate did not depend on lymphangion diameter in the rat mesentery. A correlation was found between amount of cells in the lymph flow and other indices of lymphangion functions. All microvessels with phasic contractions and/or working valve were revealed as having a lymph flow. The phasic activity and the valve work correlated with each other. The higher the amplitude and frequency of the phasic activity and the longer the contraction cycle, the higher was the rate of the valve work.